ID Q4DCI6_TRYCC Unreviewed; 592 AA.
AC Q4DCI6;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Transporter, putative {ECO:0000313|EMBL:EAN90237.1};
GN ORFNames=Tc00.1047053511469.60 {ECO:0000313|EMBL:EAN90237.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN90237.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN90237.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN90237.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN90237.1}.
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DR EMBL; AAHK01000655; EAN90237.1; -; Genomic_DNA.
DR RefSeq; XP_812088.1; XM_806995.1.
DR AlphaFoldDB; Q4DCI6; -.
DR STRING; 353153.Q4DCI6; -.
DR PaxDb; 353153-Q4DCI6; -.
DR EnsemblProtists; EAN90237; EAN90237; Tc00.1047053511469.60.
DR GeneID; 3543171; -.
DR KEGG; tcr:511469.60; -.
DR eggNOG; ENOG502QUAT; Eukaryota.
DR InParanoid; Q4DCI6; -.
DR OMA; FDIMTRT; -.
DR OrthoDB; 122529at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030001; P:metal ion transport; IEA:UniProt.
DR InterPro; IPR003445; Cat_transpt.
DR PANTHER; PTHR31064:SF30; HIGH-AFFINITY POTASSIUM TRANSPORT PROTEIN-RELATED; 1.
DR PANTHER; PTHR31064; POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED; 1.
DR Pfam; PF02386; TrkH; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 74..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 509..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 592 AA; 66784 MW; B534B02DD04AD57F CRC64;
MQRVPSADRV ASALRSRFAV NDTNSPDEPY VTLDNNAEGA TRSSQLLEYA GPVVLPLSTT
QDSIARRINF FKKWYLLMHV TYIFSIACIG SLLFYVMEDE LAYIDAFFIA ISSVCCCGLQ
TVDVATWKKS TNILRHFLMI GGGMVFTSAH QPLLRIWMLN KMWPLLEPHR DDLFLEGRLR
ASRRKYAQRL WHTSVICLLT PLLYFGIVNV TLIFLLAVFN QSNLSFLEIV EMAIASFHGS
VFLPMEQYVR DPAVVLTVTI GCGLGFTLFP VVLRGFLYAE WFTFRLVRRV RRRLLPSPHT
DLESPLAAPL SEDFPLLFSL QEREGDVLPH EFDAVDDMLH VNAWDKGFRD ILKNKHPVSF
HAFLFVRSET FYLGVAWCVI TLAQSIPFWV QQWSGDGLLA PFPTAYKIFL SVCQAAVVRF
AAASFISCLD YSNAHIAITI FCMFLPALPI PTDRTYRKWK QVFSASMVRL FTSRLFCLFL
AILCLLFGEE GWLTQELKDS RFDVMTRSFF EVISAFAGCG LSLSIPGTRV SFVGSLGMFS
KLVVAAVMLG GRHRTVDLGI DLGFSVLQAD QKMPCSVARR VSQSSPTQIN GI
//
