ID Q4DCL3_TRYCC Unreviewed; 780 AA.
AC Q4DCL3;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Nuclear pore complex protein {ECO:0000256|RuleBase:RU365072};
GN ORFNames=Tc00.1047053507771.90 {ECO:0000313|EMBL:EAN90269.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN90269.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN90269.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN90269.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- FUNCTION: Functions as a component of the nuclear pore complex (NPC).
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SUBUNIT: Part of the nuclear pore complex (NPC).
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000256|RuleBase:RU365072}. Nucleus membrane
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SIMILARITY: Belongs to the nucleoporin Nup84/Nup107 family.
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN90269.1}.
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DR EMBL; AAHK01000652; EAN90269.1; -; Genomic_DNA.
DR RefSeq; XP_812120.1; XM_807027.1.
DR AlphaFoldDB; Q4DCL3; -.
DR PaxDb; 353153-Q4DCL3; -.
DR EnsemblProtists; EAN90269; EAN90269; Tc00.1047053507771.90.
DR GeneID; 3543206; -.
DR KEGG; tcr:507771.90; -.
DR eggNOG; ENOG502QUX7; Eukaryota.
DR InParanoid; Q4DCL3; -.
DR OMA; TLTCMDG; -.
DR OrthoDB; 123092at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0017056; F:structural constituent of nuclear pore; IEA:UniProtKB-UniRule.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR007252; Nup84/Nup107.
DR PANTHER; PTHR13003:SF2; NUCLEAR PORE COMPLEX PROTEIN NUP107; 1.
DR PANTHER; PTHR13003; NUP107-RELATED; 1.
DR Pfam; PF04121; Nup84_Nup100; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU365072};
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|RuleBase:RU365072};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365072};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Translocation {ECO:0000256|ARBA:ARBA00023010,
KW ECO:0000256|RuleBase:RU365072};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365072}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 780 AA; 87592 MW; 4EF09C91442B002B CRC64;
MGNKYEEEYG KVQLPPRRSE DGGLREGMLI IRADEDYVGA AGDRENGFTP HPARAFAEIY
LQPVVRSVLT AEQFMRWSKR ELRLEEANLW SLVLELLLDA EQGSKYNPDA IGIADVQPHR
RWYVSHLSHI QELLQRHTLL RRMNIVVRWL EQTYREGNTL LKLSASRSHE EAVLLRQIIL
SHLRGGELYR AIDLAVTAGD CTYSCLLNAA QMQTVYESWF HLTPLVPLFG EYGNGEVDQV
WAGNTHRLDN LSQLYEDSVA LSNSDEGRSA IGGLDAIVAA VLCGNLEVME PAFLAAGNWK
DALWCHLRAA LVLCFTKTLM NAHHTVQPLY AGFIEKFTGS HDSWQEETAR GVVQRLSERL
QKNYLPFASL EEQLQMRVIL QFLSPGGVDW MCITDDLYTK RIDGARIISH LLLCLDTAYN
ETLHSYSVQV YSNTLAIALA QYGQQLAQMP LYSTQDAMQA VIAMNLHLRD TRQRAAVYAA
FLVACRRREL ESSSRQDVEV NEAKLVQQFC KADPVSALHD EVMRLLNQKT EPTSLLTHNT
VAEAVMWRAM HADSHEDFVV ALREALEACV SFWLAEPHAE LDAISDVSGI LRRNILPYLQ
EKNETLGDME LIEAHFWIKF AEVRSTADEH ARSTAQLDVA LGGGDRTLVF QLAQDESALL
RELHALTQEA LSHGGALVRR SRSCVTAVTW IVQVFAEEVA LSVRLASPGA SVMMEQLRKV
FALVEQLDGL GYIDPNLIPR QSARELFDAV RAARVACGQK SHDLLVSEAK KTAAARQLPL
//
