ID Q4DE68_TRYCC Unreviewed; 712 AA.
AC Q4DE68;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Leucine-rich repeat protein (LRRP) {ECO:0008006|Google:ProtNLM};
GN ORFNames=Tc00.1047053506493.40 {ECO:0000313|EMBL:EAN90815.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN90815.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN90815.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN90815.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- SIMILARITY: Belongs to the PPP1R37 family.
CC {ECO:0000256|ARBA:ARBA00038315}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN90815.1}.
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DR EMBL; AAHK01000584; EAN90815.1; -; Genomic_DNA.
DR RefSeq; XP_812666.1; XM_807573.1.
DR AlphaFoldDB; Q4DE68; -.
DR SMR; Q4DE68; -.
DR STRING; 353153.Q4DE68; -.
DR PaxDb; 353153-Q4DE68; -.
DR EnsemblProtists; EAN90815; EAN90815; Tc00.1047053506493.40.
DR GeneID; 3543925; -.
DR KEGG; tcr:506493.40; -.
DR eggNOG; ENOG502S0G8; Eukaryota.
DR InParanoid; Q4DE68; -.
DR OrthoDB; 164107at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0005929; C:cilium; IEA:UniProt.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24112; LEUCINE-RICH REPEAT, ISOFORM F-RELATED; 1.
DR PANTHER; PTHR24112:SF66; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37; 1.
DR Pfam; PF13516; LRR_6; 5.
DR SMART; SM00367; LRR_CC; 5.
DR SMART; SM00368; LRR_RI; 8.
DR SUPFAM; SSF52047; RNI-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 712 AA; 77776 MW; 70D3812201752D49 CRC64;
MRRVAKHANA AISTMRWLWT LHDLAACPSI DVLRLHMCQR AQQETEWDLD FALLSSLNKS
HAPNEVLRCC CAAISSAAQS VERIAVTVTS AAVGGALARV LCSAQAESLR ILHLTLHEAA
FLRDYLALAT LLRSTAHFTS NLNSLCITMV ACDMQHGLQW NQKSLRALAA NIPSLTLRVL
SLEYINLQGA NENDLMVLCE AIAHCHLLTH LSLRGTRGLL PRVPLLRVAV AQMRRLEVLD
LSSTLLGDVV MEQLVDTLRM SIGGCCRLRQ LNLLETNVSV WGLRRLLRDV GEMSHGETAK
IELLNFSSNS MDDEGAFVLA SVCMHCGMLR ELHLRHNRLT KKGAADVGSA LIAAASLRCL
NLHSNPLSDE GLFALLQYAK YWPELRSLDF TRCRLTARCL PALCAALPLF DRLEEISLDR
NDLRVIDAGD ASNTEDKRET PEGDLPLFAY DPKFMQSGSR GDWKVSTSFE LDRRDAIEGR
RRFKGTESFQ TPLSSRESIG GVVPFEQLGL ALSGCRELGR LSLSSCSLTD DCFLAMAGAL
VVRRLTHLDL SANPLFTRME SLEALAKLLR RASASMQKLD LSCTGLGSVG ASLLVDGSPT
DDTNGDADEA VSALRSLTAL TELRFSSCRI GAEGFEAIAD AFPAMTLLER VFLDGNAVQK
LDVILYLLSA LEALPSLRFV GLYGSVPPHL AATVGASREY AALQSKGVVV HL
//
