ID Q4DEW3_TRYCC Unreviewed; 1046 AA.
AC Q4DEW3;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=BTB domain-containing protein {ECO:0000259|PROSITE:PS50097};
GN ORFNames=Tc00.1047053510531.30 {ECO:0000313|EMBL:EAN91060.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN91060.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN91060.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN91060.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN91060.1}.
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DR EMBL; AAHK01000560; EAN91060.1; -; Genomic_DNA.
DR RefSeq; XP_812911.1; XM_807818.1.
DR AlphaFoldDB; Q4DEW3; -.
DR SMR; Q4DEW3; -.
DR PaxDb; 353153-Q4DEW3; -.
DR EnsemblProtists; EAN91060; EAN91060; Tc00.1047053510531.30.
DR GeneID; 3544210; -.
DR KEGG; tcr:510531.30; -.
DR eggNOG; KOG0379; Eukaryota.
DR InParanoid; Q4DEW3; -.
DR OrthoDB; 163164at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR CDD; cd18186; BTB_POZ_ZBTB_KLHL-like; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR46093; ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5; 1.
DR PANTHER; PTHR46093:SF17; MULTIPLE EGF-LIKE-DOMAINS 8; 1.
DR Pfam; PF13418; Kelch_4; 1.
DR Pfam; PF13854; Kelch_5; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 827..923
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 18..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1046 AA; 114777 MW; FF27ED42353CBED6 CRC64;
MRDSVDASEI KALLQELEGV VGSPTTTKEE NERPFSPKKR GSSNVDVAVS RYAGHLGQSK
FSTYANTTND SRRAVVPLWE RLPPVNTVDI TGDASCPVKS PVTASQKTFL RPKLVGGAVG
ASLQRMPLEG KVNNASPPKN DEQGLQQTKL TSQKQIQGEE KEPPTTSFSK EPLAQGEGEG
EDREREVNFL PIMCARYINP AGITPRARWG HTLTPMQGQK LLLFGGMEIE EGETASLFEY
DTHHISWDPV CVSGGVTPTP RTNHAACASG GRWLYISGGT TDRGTRILGD LYCYDIFTQE
WTCLWEYGGS STRSKHEPTP RFGHSMVSWE DRLYIFGGKT PKRDQGDSQS TQHVTVASTD
VYVFSLTSRK WKRRIHAGKT MGLNGDGKNI LNNRKPEETP LPAAPSVTQL TNVFSERPAN
RFFHAACVLG DCMYINGGTG DGGVILSDTW FLDLRKQHWV LLHNGRTADS FPREKHHLFA
CGEALLVVGG CSASSHSTRI TLKYHNFVAV LPFEGNDSPC WIPVAMGNVS IVAPNRKSFG
AAFAGGFVHV FGGVSGSEPA SNSMVRFLAA DGYFETDSRS WAKSNADALT SMMRHIREAS
ISTMFDTYAI PRSWDGETGI DTLSNRPYGV HRGFLQQRAP KFWEDLKRCR MEHVKPAGTG
SAMPSLDLTD PLKDAFTPSP VFSTTGGVAT TSTAAGETHP SHAVAYFTEG NSRIQGLSVS
LSAEQLQCLL DYIYWGDVRH RILLEQEEEE YTKDANVSGQ GDAMQEEAKV LQALRHAADV
YDLNPLMDIC DALLARSRKK LKQAHERSTR QLQADLLSLL ESSNSATATV LFVDPHTKQK
SVYSLHPFIL MAASSFFNDL LRPLVSGEKT TFQVGPVAAK MRSAGRGSSQ TRRDILVGPV
SVPYLAVKPL LRFLYTQRLT VPREAVFATL LGSHLLDVAP LQAYCESILA REEVNYDTAG
QFYSLGRKYH APLLQETALL TAVLGYAEVC RSPAYKALSE KEAREIDAVA HELGATSWIA
PPQAVSEVKP AAVYQLRWNA SSPLSK
//
