ID Q4DGK7_TRYCC Unreviewed; 508 AA.
AC Q4DGK7;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN ORFNames=Tc00.1047053511257.40 {ECO:0000313|EMBL:EAN91656.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN91656.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN91656.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN91656.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN91656.1}.
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DR EMBL; AAHK01000505; EAN91656.1; -; Genomic_DNA.
DR RefSeq; XP_813507.1; XM_808414.1.
DR AlphaFoldDB; Q4DGK7; -.
DR STRING; 353153.Q4DGK7; -.
DR PaxDb; 353153-Q4DGK7; -.
DR EnsemblProtists; EAN91656; EAN91656; Tc00.1047053511257.40.
DR GeneID; 3544889; -.
DR KEGG; tcr:511257.40; -.
DR eggNOG; KOG0230; Eukaryota.
DR InParanoid; Q4DGK7; -.
DR OMA; CAVIDCA; -.
DR OrthoDB; 122853at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23164; EARLY ENDOSOME ANTIGEN 1; 1.
DR PANTHER; PTHR23164:SF31; INACTIVE SERINE_THREONINE-PROTEIN KINASE SLOB1-RELATED; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 9..118
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 201..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 508 AA; 55389 MW; F99D0D305F51A394 CRC64;
MYMAQWKPDN ASKKCDSCAK RFEIFRRRHH CRICGGLFCY SCSNVFLPVE RILMRWLEMN
WYGETIRKMA AIDTKTSENG PPTTMEKRLA TLLGSSGALE PATKALQRVC VQCFEDVETY
SSSIKKSLSR QGCRDSNLGA ASSGDYPGGW KCWRDKHFSL FGGRERKVCV ILLQDSGVVE
SGERTNLREL FHALEQLTNE ANARTTQGQT SSKDTTPSLG PSLSSVSDIS ESEKNSFETS
IGREGTTATT IMMQQSALRC PLSKGTPTKY RKKIVLQVPI PLNTSDSTAR VSSMVTANLS
VRMQLVGVTH RQGFDKALLQ QHTIGTDAYI IFLDGELVST VDTTAMTGAS NGIGNAVSGS
YMAPHLKNPF PSPIVSLFPP SYDSPQEPTP DAMTSTICAA YDRSVSGKLM ETARGVWEAI
GRYGGDIPIC AVIDCTSCIG AGSMELGTVS SSTGCNKNPQ TGGSANLRCL KDKQQRSVPV
ETQASALQKA LLLLSEEVIR RDMLRRKG
//
