ID Q4DQK3_TRYCC Unreviewed; 731 AA.
AC Q4DQK3;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=FCP1 homology domain-containing protein {ECO:0000259|PROSITE:PS50969};
GN ORFNames=Tc00.1047053507677.140 {ECO:0000313|EMBL:EAN94814.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN94814.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN94814.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN94814.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN94814.1}.
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DR EMBL; AAHK01000251; EAN94814.1; -; Genomic_DNA.
DR RefSeq; XP_816665.1; XM_811572.1.
DR AlphaFoldDB; Q4DQK3; -.
DR STRING; 353153.Q4DQK3; -.
DR PaxDb; 353153-Q4DQK3; -.
DR EnsemblProtists; EAN94814; EAN94814; Tc00.1047053507677.140.
DR GeneID; 3548589; -.
DR KEGG; tcr:507677.140; -.
DR eggNOG; KOG1605; Eukaryota.
DR InParanoid; Q4DQK3; -.
DR OMA; WKKAARY; -.
DR OrthoDB; 128499at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR004274; FCP1_dom.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR PANTHER; PTHR12210; DULLARD PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR12210:SF115; FCP1 HOMOLOGY DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03031; NIF; 1.
DR SMART; SM00577; CPDc; 1.
DR SUPFAM; SSF56784; HAD-like; 2.
DR PROSITE; PS50969; FCP1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT DOMAIN 365..557
FT /note="FCP1 homology"
FT /evidence="ECO:0000259|PROSITE:PS50969"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 692..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..135
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..447
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 731 AA; 79395 MW; BA95A2A33701D43A CRC64;
MTRFAVGTRN SDKTCRKRRQ EEVNSSKKKD VATAVVKEAP DGEGPFLPHN TPDEGGRESL
PSVSRPVVNL LDVVAEEDSL TPTAARDAAG GGCKGSKGGK KGKTTAMKSD DAGKKRVLSG
TSPKKGKAKQ RSKASKTKPG KAERGGESSV ANAGKGQGEA DSKKENDDHA LSLRQQIPEM
NNIPVKVHLV EHDISELQID RTSCRNGTSS SRLNPSRDLS SFNDCLEEMN SCDFISNNNS
NKNGLSNNSN EGFLSLKEQD AAEKPLSLRY SVMPPLTIPR EGRKEHTQQK DGASKNASVH
ASRAPSAPSV SLVSGNSSGA DTNGEKFARR SAHSSLEEAL DGLLPKNILY PTRQLLTRSL
ASAAEKERTA TIVFDLDETL CNNRQHGPAI LRPGAVEMLK QLRALYPHPV MHKGETPMEP
TGKNSSTQVL EGGKDNGIQN RSPEATETPT DDGVMLRLEI IIWTASVEVV ARPVIARLDP
DGTILDDVIY RDVRWYRDGG YTKDLRRIGR HLERNVIVEN APSCVCMNRR NAILVNDFVS
NPADRQLVIV RAILQEWLYN VNALLVHWHF QKLKQKRHNM IEDGGESPEP DKPMITPLTR
GGSAHSSVSR SKGELSLLSS SHGGGNLLQE LEQKASAIHF LTHHPFLSPG TRYVKPSVWK
KAARYLHGCA GSNTAAAKPL MAMPAAMAGE LGGGRGPQEL PATTPARPVV SARPRGHRSF
VDMARGPREV R
//
