ID Q4DS34_TRYCC Unreviewed; 422 AA.
AC Q4DS34;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 24-JAN-2024, entry version 74.
DE SubName: Full=Phosphoinositide-binding protein, putative {ECO:0000313|EMBL:EAN95323.1};
GN ORFNames=Tc00.1047053510657.30 {ECO:0000313|EMBL:EAN95323.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN95323.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN95323.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN95323.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN95323.1}.
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DR EMBL; AAHK01000219; EAN95323.1; -; Genomic_DNA.
DR RefSeq; XP_817174.1; XM_812081.1.
DR AlphaFoldDB; Q4DS34; -.
DR SMR; Q4DS34; -.
DR STRING; 353153.Q4DS34; -.
DR PaxDb; 353153-Q4DS34; -.
DR EnsemblProtists; EAN95323; EAN95323; Tc00.1047053510657.30.
DR GeneID; 3549192; -.
DR KEGG; tcr:510657.30; -.
DR eggNOG; KOG2273; Eukaryota.
DR InParanoid; Q4DS34; -.
DR OMA; WSLHRFI; -.
DR OrthoDB; 5488895at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd07596; BAR_SNX; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR015404; Vps5_C.
DR PANTHER; PTHR10555:SF170; FI18122P1; 1.
DR PANTHER; PTHR10555; SORTING NEXIN; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF09325; Vps5; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT DOMAIN 1..134
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT COILED 306..360
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 422 AA; 48359 MW; 0D2F4703C9015171 CRC64;
MGETVFEFKV LDPEQRRGTG ALDLAYWTYR IRASTTLSTY AQKDLEVVRR YSDFEWFRAQ
LCEAYPYCIV PPIPEKDVQG TLDKIVGSGS QSASRLRDYR QRALRKFLVR LGAHPRLHTS
HLLKDFLEMN EDEWERKMKA SAKNSEGFFT SSLGEGVNHA FTRQWNTSGA VAEAGAAYTR
VVTNTNTTPQ VWEETRLYIQ QLEDSIKMLR ERLQLLVDRR RNTSNALHEF GVAFEKVGEI
ERGIESTPLS NALIAVGQHS EQLFFIYSDY ANEEMKQVVE TLNYYCGMCA AVRETLRRVH
NRSHYVESLR QHAAEVVAQK ERALEKGGQA GRVARLESEL AGLEDRLSTA KRELEAGETI
LKDELRRFHQ EKQYDVKAIL KNFAELQLKY AARMKETWES LRPTVEAVQF EGEGGGQGNA
LR
//
