ID Q4E128_TRYCC Unreviewed; 349 AA.
AC Q4E128;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 24-JAN-2024, entry version 93.
DE SubName: Full=Replication factor C, subunit 5, putative {ECO:0000313|EMBL:EAN98490.1};
GN ORFNames=Tc00.1047053506247.270 {ECO:0000313|EMBL:EAN98490.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN98490.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN98490.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN98490.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN98490.1}.
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DR EMBL; AAHK01000054; EAN98490.1; -; Genomic_DNA.
DR RefSeq; XP_820341.1; XM_815248.1.
DR AlphaFoldDB; Q4E128; -.
DR SMR; Q4E128; -.
DR STRING; 353153.Q4E128; -.
DR PaxDb; 353153-Q4E128; -.
DR EnsemblProtists; EAN98490; EAN98490; Tc00.1047053506247.270.
DR GeneID; 3552988; -.
DR KEGG; tcr:506247.270; -.
DR eggNOG; KOG2035; Eukaryota.
DR InParanoid; Q4E128; -.
DR OMA; LMCEACK; -.
DR OrthoDB; 868at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR PANTHER; PTHR11669:SF1; REPLICATION FACTOR C SUBUNIT 3; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT DOMAIN 33..187
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 349 AA; 39169 MW; 347C20BEF15F4011 CRC64;
MLWVDKYRPK SLVEVELYPE LTEVLKRLAE SQDLPHLLLY GPSGTGKKTR AMAVLHHVYG
PSVYSLRLEH RSVQVTDSKV VDIATLSSPH HIDINPSDAG NYDRVIVMQM IREIAQTVSL
QSSTSNGVKY KVVLLNEVDK MGRAAQHALR RTMEKYMSTC RLVLICNSTS RLIAPLRSRC
LAVRVPSHSK ENLTKVIRGV CERENRPLPS PEFMATVTQR SEGNLRRALL MVEAAAMTKV
DFSGNGADIP QPDWRVFLDE IANDILSEQT PKKLHEIRGK FYNLLGQCVS GELILRLVLE
KLMSAVDPAL RRPLVALAAQ YDHNMKLGTK TIVHLEAFAA GVMQLLKQK
//
