ID Q4E1M0_TRYCC Unreviewed; 723 AA.
AC Q4E1M0;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE RecName: Full=Cell division control protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=Tc00.1047053508909.40 {ECO:0000313|EMBL:EAN98652.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN98652.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN98652.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN98652.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- SIMILARITY: Belongs to the CEF1 family.
CC {ECO:0000256|ARBA:ARBA00010506}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN98652.1}.
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DR EMBL; AAHK01000046; EAN98652.1; -; Genomic_DNA.
DR RefSeq; XP_820503.1; XM_815410.1.
DR AlphaFoldDB; Q4E1M0; -.
DR SMR; Q4E1M0; -.
DR STRING; 353153.Q4E1M0; -.
DR PaxDb; 353153-Q4E1M0; -.
DR EnsemblProtists; EAN98652; EAN98652; Tc00.1047053508909.40.
DR GeneID; 3553211; -.
DR KEGG; tcr:508909.40; -.
DR eggNOG; KOG0050; Eukaryota.
DR InParanoid; Q4E1M0; -.
DR OMA; NINEAWT; -.
DR OrthoDB; 131128at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0000974; C:Prp19 complex; IEA:InterPro.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd00167; SANT; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR047242; CDC5L/Cef1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR PANTHER; PTHR45885; CELL DIVISION CYCLE 5-LIKE PROTEIN; 1.
DR PANTHER; PTHR45885:SF1; CELL DIVISION CYCLE 5-LIKE PROTEIN; 1.
DR Pfam; PF13921; Myb_DNA-bind_6; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
DR PROSITE; PS50090; MYB_LIKE; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 3..58
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 3..54
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 61..115
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 61..111
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT REGION 230..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 324..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 670..715
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 494..516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 723 AA; 82302 MW; 28F27E316D472E9D CRC64;
MSRIRFKGGA WTNSEDEVLR ASLTVYGLQN WERVASMLVR KTAAQCRERW ENYLDPRLHI
REAWTAEEEE QLVQLQSLFT NQWNLIAREL RHRTGMNRPA WLCEEHYHTL LDALEYERQQ
KEGGNNKRNE SLTLEDFLAE RRRHRAYHQG HETRASKADA VNSDVFEKEM VEFAVSRLAN
QDGKKGLRKE RKKQLQHTSF LAKLQSNREA IESGTLSAKA KKRMERAMLE ERAGPSDTRL
QDEILEDDDV GSSGGSDVGN DESKRGQKGV FRPIDLGADK QEAGIQAKHR ELVKNLSADM
TRLQQEATVS EGINVELLRL ASGTSGSANR QVEDKKKTPP ITSKSSAAPG ASPDTADLDH
LFASLPEAIL PEQESVVGAR ASVDELFGTL PEPLLGGRVS KDKFNVAVAT PEDYEAEEEE
EAEVSYTVSP SEPSQAPLTA LNFSTEEGRS WLREAKRRVL VESESVFLNR KRVRHHMSSP
TEKTQLMMTT KNGEEEKGQL EGERKEKEEK NDDNDESTWC IVRALVEQQL PATARDLLEA
KAVPDGFLAK KAKREEDSSA RYNNTQEYVK EKGGNEEEKD TTIELAACVA AVQDEDGADF
WKDVGATEAT VQLEELVHHQ REQVAANTAN DTEAYQHLER MVRICFAGSR KELRGEDIIN
RVCVYWGWRL EEAQRRLAFY SAIREVERQE MQRRINDATS RLTEIEQKER TLQERYRSMR
LAE
//
