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Database: UniProt
Entry: Q4ECJ5_9RICK
LinkDB: Q4ECJ5_9RICK
Original site: Q4ECJ5_9RICK 
ID   Q4ECJ5_9RICK            Unreviewed;       464 AA.
AC   Q4ECJ5;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   16-JAN-2019, entry version 91.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:EAL59173.1};
GN   ORFNames=WwAna1629 {ECO:0000313|EMBL:EAL59173.1};
OS   Wolbachia endosymbiont of Drosophila ananassae.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Wolbachieae; Wolbachia.
OX   NCBI_TaxID=307502 {ECO:0000313|EMBL:EAL59173.1};
RN   [1] {ECO:0000313|EMBL:EAL59173.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15774024; DOI=10.1186/gb-2005-6-3-r23;
RA   Salzberg S.L., Hotopp J.C., Delcher A.L., Pop M., Smith D.R.,
RA   Eisen M.B., Nelson W.C.;
RT   "Serendipitous discovery of Wolbachia genomes in multiple Drosophila
RT   species.";
RL   Genome Biol. 6:R23-R23(2005).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EAL59173.1}.
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DR   EMBL; AAGB01000013; EAL59173.1; -; Genomic_DNA.
DR   ProteinModelPortal; Q4ECJ5; -.
DR   EnsemblBacteria; EAL59173; EAL59173; WwAna1629.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      162    291       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      373    442       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     170    177       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      325    345       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   464 AA;  53386 MW;  018E6D579DD09CD3 CRC64;
     MVWYMNLTSP KVSTMFFDQI ITVTDHNVTW EKIQNCLYNL YGEATYNSWL SSLKFVSSRN
     GEVLLSVSTR FIKEWITVHY MKKILSLWQS EDKSIRSIDI QVIEERNSNF NVILKNREES
     NHNLGSPLDP RFTFDNFVVG KPNELAFTAA KRVAESIDPI LGSNPLFLYG GVGLGKTHLM
     HAIAWHIVNS PSAKRKVVYL SAEKFMYQYI TALRSKDIML FKEQFRSVDV LMVDDVQFIS
     GKDSTQEEFF HTFNALIDQN KQLVISADRS PSDLDGVEER IKSRLGWGLV ADINETTFEL
     RLGILQAKVE QMNMYVPKDV LEFLARNIKS NIRELEGALN KVTHTSLIGR SMTVESASET
     LIDLLRSNHR SVTIEEIQKK VAEFFNIKVA DMQSNRRLRS LARPRQIAMY FAKKFTQKSL
     PDIGRNFGGR DHATVIHAVK QVENFIKTDS KFADEINRLK KMFK
//
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