ID   Q4FSC1_PSYA2            Unreviewed;       844 AA.
AC   Q4FSC1;
DT   30-AUG-2005, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2005, sequence version 1.
DT   27-MAR-2024, entry version 116.
DE   SubName: Full=Quinoprotein glucose dehydrogenase {ECO:0000313|EMBL:AAZ19087.1};
DE            EC=1.1.5.2 {ECO:0000313|EMBL:AAZ19087.1};
GN   OrderedLocusNames=Psyc_1237 {ECO:0000313|EMBL:AAZ19087.1};
OS   Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Psychrobacter.
OX   NCBI_TaxID=259536 {ECO:0000313|EMBL:AAZ19087.1, ECO:0000313|Proteomes:UP000000546};
RN   [1] {ECO:0000313|EMBL:AAZ19087.1, ECO:0000313|Proteomes:UP000000546}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17307 / VKM B-2377 / 273-4
RC   {ECO:0000313|Proteomes:UP000000546};
RX   PubMed=20154119; DOI=10.1128/AEM.02101-09;
RA   Ayala-del-Rio H.L., Chain P.S., Grzymski J.J., Ponder M.A., Ivanova N.,
RA   Bergholz P.W., Di Bartolo G., Hauser L., Land M., Bakermans C.,
RA   Rodrigues D., Klappenbach J., Zarka D., Larimer F., Richardson P.,
RA   Murray A., Thomashow M., Tiedje J.M.;
RT   "The genome sequence of Psychrobacter arcticus 273-4, a psychroactive
RT   Siberian permafrost bacterium, reveals mechanisms for adaptation to low-
RT   temperature growth.";
RL   Appl. Environ. Microbiol. 76:2304-2312(2010).
CC   -!- COFACTOR:
CC       Name=pyrroloquinoline quinone; Xref=ChEBI:CHEBI:58442;
CC         Evidence={ECO:0000256|ARBA:ARBA00001931};
CC   -!- SIMILARITY: Belongs to the bacterial PQQ dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00008156}.
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DR   EMBL; CP000082; AAZ19087.1; -; Genomic_DNA.
DR   RefSeq; WP_011280509.1; NC_007204.1.
DR   AlphaFoldDB; Q4FSC1; -.
DR   STRING; 259536.Psyc_1237; -.
DR   KEGG; par:Psyc_1237; -.
DR   eggNOG; COG4993; Bacteria.
DR   HOGENOM; CLU_018478_1_0_6; -.
DR   OrthoDB; 9794322at2; -.
DR   Proteomes; UP000000546; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   GO; GO:0008876; F:quinoprotein glucose dehydrogenase activity; IEA:UniProtKB-EC.
DR   CDD; cd10280; PQQ_mGDH; 1.
DR   Gene3D; 2.140.10.10; Quinoprotein alcohol dehydrogenase-like superfamily; 2.
DR   InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR   InterPro; IPR017511; PQQ_mDH.
DR   InterPro; IPR002372; PQQ_repeat.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   NCBIfam; TIGR03074; PQQ_membr_DH; 1.
DR   PANTHER; PTHR32303; QUINOPROTEIN ALCOHOL DEHYDROGENASE (CYTOCHROME C); 1.
DR   PANTHER; PTHR32303:SF4; QUINOPROTEIN GLUCOSE DEHYDROGENASE; 1.
DR   Pfam; PF13360; PQQ_2; 1.
DR   SMART; SM00564; PQQ; 5.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:AAZ19087.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000546};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        5..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        30..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        54..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        76..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..149
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          169..190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        169..184
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   844 AA;  91080 MW;  B2D4F11527C120D6 CRC64;
     MEKFVAIIMA VFAAPLLIGG AYLLSLGGSP YYLFAGIVML ATAFLLFKKH WSAYGLYAIF
     IVATIAWALW ESGFYWWALA PRVGFPLIFG LLMLLPWVSN KMRGQRAQVA TSTANSAITP
     NTVKKNPLYY WGLLASVVVG ALLSFGSLAN NATDKLGELD LSASDKDTST NLGDSLSTGE
     QTPDGEWSAY GRTDYGQRYS PLTQITTDNV KDLELAWQIQ TGDVKGPNDV GETTYQATPL
     KIGNALYLCT PHNWVMALDA DSGETLWKFD PKVEKNLQRQ HQTCRGVSYY AGQSGTDSTP
     PVANNETSST ISNAAVSNQP AATSDMIVQK IAGNTFENAS KQCDAKIFIP TSDAKLYALD
     PNTGQRCQDF GEDGALDLMH NMPFTQAGYY YSTSPPIVVG NTIVVAGAVN DNYDVNSPSG
     VIRAYDVNTG ELLWNWDSGD PDNTAPFDVN DPTQTYKTSS PNSWAIASAD EELGLVYFPM
     GNRTPDQLGS YRNAAEEKYA TSVVALDINT GEARWVQQFV HHDLWDMDTP AQPTLLDLDT
     ADGVQPALVV PTKQGDVYVL NRATGEPIVP IKERDAPQGY LIAGEHAAPT QPYSGLSFEP
     PMLKEKDMWG ASLIDQMMCR IEFNQLNYDG RYTPPSTNGS IVYPGNFGTF NWGGIAVDPE
     NGVMFGMPTY LAFTSKLIPK ETLGDVETNK GEQGVNANEG ADYAVEMGPF LSPLGVPCQQ
     PPWGTIAGAD LATGEIAYQR KNGTVQDLSP IPLKLELGVP GIGGPIITKG GVALLSAATE
     NNFRAYDLKN GDVLWNVRIP AGGQATPMTY LNSKGEQMVV LVAGGHGSVG TTIGDYVMAY
     KLAK
//