ID   Q4J6F5_SULAC            Unreviewed;       400 AA.
AC   Q4J6F5;
DT   02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT   02-AUG-2005, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=NADH-ubiquinone oxidoreductase {ECO:0000313|EMBL:AAY81626.1};
DE            EC=1.6.5.3 {ECO:0000313|EMBL:AAY81626.1};
GN   OrderedLocusNames=Saci_2344 {ECO:0000313|EMBL:AAY81626.1};
OS   Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC
OS   15157 / NCIMB 11770).
OC   Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=330779 {ECO:0000313|EMBL:AAY81626.1, ECO:0000313|Proteomes:UP000001018};
RN   [1] {ECO:0000313|EMBL:AAY81626.1, ECO:0000313|Proteomes:UP000001018}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770
RC   {ECO:0000313|Proteomes:UP000001018};
RX   PubMed=15995215; DOI=10.1128/JB.187.14.4992-4999.2005;
RA   Chen L., Brugger K., Skovgaard M., Redder P., She Q., Torarinsson E.,
RA   Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
RT   "The genome of Sulfolobus acidocaldarius, a model organism of the
RT   Crenarchaeota.";
RL   J. Bacteriol. 187:4992-4999(2005).
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DR   EMBL; CP000077; AAY81626.1; -; Genomic_DNA.
DR   RefSeq; WP_011279128.1; NZ_CP046615.1.
DR   AlphaFoldDB; Q4J6F5; -.
DR   STRING; 330779.Saci_2344; -.
DR   GeneID; 78440329; -.
DR   KEGG; sai:Saci_2344; -.
DR   PATRIC; fig|330779.12.peg.2351; -.
DR   eggNOG; arCOG01548; Archaea.
DR   HOGENOM; CLU_015134_1_2_2; -.
DR   Proteomes; UP000001018; Chromosome.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   Gene3D; 1.10.645.10; Cytochrome-c3 Hydrogenase, chain B; 1.
DR   InterPro; IPR001135; NADH_Q_OxRdtase_suD.
DR   InterPro; IPR022885; NDH1_su_D/H.
DR   InterPro; IPR029014; NiFe-Hase_large.
DR   PANTHER; PTHR11993:SF10; NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11993; NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT; 1.
DR   Pfam; PF00346; Complex1_49kDa; 1.
DR   SUPFAM; SSF56762; HydB/Nqo4-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000313|EMBL:AAY81626.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001018};
KW   Ubiquinone {ECO:0000313|EMBL:AAY81626.1}.
FT   DOMAIN          131..400
FT                   /note="NADH-quinone oxidoreductase subunit D"
FT                   /evidence="ECO:0000259|Pfam:PF00346"
SQ   SEQUENCE   400 AA;  45812 MW;  60B0D615BDD8071E CRC64;
     MTSQLEPSFG VEIIPVEGEL NVGPQHPGSG HMRIYVKLNG DIIEDVDLDV GYVHRSVEKL
     SEVRNYMHLI PLIERPAILD SIHMNLGYIM AVEKILNVDV PERAQYLRTL VAEVNRIASH
     LYGMGILAIF LGHSTGFMWG FGDREVWVEI LQAITGARVT NSYIIPGGVR RDLTPAIKEM
     IEKAIVYQRK KIQDWYKILV NNPNIRARLE NVGVMSKENA IKWGAVGPNL RASGVYYDVR
     KIEPYGAYDK VDFEIPMYKE GDAYARTLVR FEEMEQSMRI LEQVIKQIPD GNILSDRFFK
     QIPPVRLKKW WEGQRRVVFP GYYASFRPPK GEAISRVEAG RGELAYYIIS DGSPKPYRLR
     MITPSYRLIY VFKELCKGAR YADLVAIYGS LDYFPPEADR
//