ID Q4JA55_SULAC Unreviewed; 392 AA.
AC Q4JA55;
DT 02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 02-AUG-2005, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:AAY80325.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:AAY80325.1};
GN OrderedLocusNames=Saci_0963 {ECO:0000313|EMBL:AAY80325.1};
OS Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC
OS 15157 / NCIMB 11770).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=330779 {ECO:0000313|EMBL:AAY80325.1, ECO:0000313|Proteomes:UP000001018};
RN [1] {ECO:0000313|EMBL:AAY80325.1, ECO:0000313|Proteomes:UP000001018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770
RC {ECO:0000313|Proteomes:UP000001018};
RX PubMed=15995215; DOI=10.1128/JB.187.14.4992-4999.2005;
RA Chen L., Brugger K., Skovgaard M., Redder P., She Q., Torarinsson E.,
RA Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
RT "The genome of Sulfolobus acidocaldarius, a model organism of the
RT Crenarchaeota.";
RL J. Bacteriol. 187:4992-4999(2005).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982}.
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DR EMBL; CP000077; AAY80325.1; -; Genomic_DNA.
DR RefSeq; WP_011277827.1; NZ_CP046615.1.
DR AlphaFoldDB; Q4JA55; -.
DR STRING; 330779.Saci_0963; -.
DR GeneID; 78441310; -.
DR KEGG; sai:Saci_0963; -.
DR PATRIC; fig|330779.12.peg.924; -.
DR eggNOG; arCOG01282; Archaea.
DR HOGENOM; CLU_031026_0_0_2; -.
DR Proteomes; UP000001018; Chromosome.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:AAY80325.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001018};
KW Transferase {ECO:0000313|EMBL:AAY80325.1}.
FT DOMAIN 4..262
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 270..390
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
SQ SEQUENCE 392 AA; 42551 MW; 9BD8667BEE3D02F5 CRC64;
MDNVYIVSAV RTPLGKFGGS LKDISPSELG SVVIREAVNR AKVDPKLIDI VIMGNVLRAG
HGQDLARQAS IKAGIPAKTD AYCVDMVCSS GMISTINAVQ MIKSEDADIV VAGGMESMSR
ASFAIGSEIR WGTKMLMNKS LDIIDTMIID GLTDPFNFKV MGQEADMVAR EHEITRRELD
EVAYESHRRA TIATEKGYFK DEIVPLNVDG RVVDKDEGIR ADTTLEKLLQ LKPAFGSDGL
HTAGNSSQIS DGAAALVFVS ESAVRKFKLE PIARVLGYSW IGIESWKFPE APIYSVKKLL
DKINIPLSKF DYFENNEAFA VNNVLFNRYL GVSYDRLNVY GGAIALGHPI GASGSRILVT
LLNVLRKMNG KYGIASICHG IGGSTAIAVE LL
//
