ID Q4N0M7_THEPA Unreviewed; 327 AA.
AC Q4N0M7;
DT 02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 02-AUG-2005, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE RecName: Full=Cyclin-dependent kinases regulatory subunit {ECO:0000256|RuleBase:RU311113};
GN OrderedLocusNames=TP03_0089 {ECO:0000313|EMBL:EAN30825.1};
OS Theileria parva (East coast fever infection agent).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=5875 {ECO:0000313|EMBL:EAN30825.1, ECO:0000313|Proteomes:UP000001949};
RN [1] {ECO:0000313|EMBL:EAN30825.1, ECO:0000313|Proteomes:UP000001949}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Muguga {ECO:0000313|EMBL:EAN30825.1,
RC ECO:0000313|Proteomes:UP000001949};
RX PubMed=15994558; DOI=10.1126/science.1110439;
RA Gardner M.J., Bishop R., Shah T., de Villiers E.P., Carlton J.M., Hall N.,
RA Ren Q., Paulsen I.T., Pain A., Berriman M., Wilson R.J.M., Sato S.,
RA Ralph S.A., Mann D.J., Xiong Z., Shallom S.J., Weidman J., Jiang L.,
RA Lynn J., Weaver B., Shoaibi A., Domingo A.R., Wasawo D., Crabtree J.,
RA Wortman J.R., Haas B., Angiuoli S.V., Creasy T.H., Lu C., Suh B.,
RA Silva J.C., Utterback T.R., Feldblyum T.V., Pertea M., Allen J.,
RA Nierman W.C., Taracha E.L.N., Salzberg S.L., White O.R., Fitzhugh H.A.,
RA Morzaria S., Venter J.C., Fraser C.M., Nene V.;
RT "Genome sequence of Theileria parva, a bovine pathogen that transforms
RT lymphocytes.";
RL Science 309:134-137(2005).
CC -!- FUNCTION: Binds to the catalytic subunit of the cyclin dependent
CC kinases and is essential for their biological function.
CC {ECO:0000256|RuleBase:RU311113}.
CC -!- SIMILARITY: Belongs to the CKS family. {ECO:0000256|RuleBase:RU311113}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN30825.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAGK01000005; EAN30825.1; -; Genomic_DNA.
DR RefSeq; XP_763108.1; XM_758015.1.
DR AlphaFoldDB; Q4N0M7; -.
DR STRING; 5875.Q4N0M7; -.
DR EnsemblProtists; EAN30825; EAN30825; TP03_0089.
DR GeneID; 3500030; -.
DR KEGG; tpv:TP03_0089; -.
DR VEuPathDB; PiroplasmaDB:TpMuguga_03g00089; -.
DR eggNOG; ENOG502SUIZ; Eukaryota.
DR InParanoid; Q4N0M7; -.
DR Proteomes; UP000001949; Unassembled WGS sequence.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.170.10; Cyclin-dependent kinase, regulatory subunit; 1.
DR InterPro; IPR000789; Cyclin-dep_kinase_reg-sub.
DR InterPro; IPR036858; Cyclin-dep_kinase_reg-sub_sf.
DR Pfam; PF01111; CKS; 1.
DR SMART; SM01084; CKS; 1.
DR SUPFAM; SSF55637; Cell cycle regulatory proteins; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|RuleBase:RU311113};
KW Cell division {ECO:0000256|RuleBase:RU311113};
KW Reference proteome {ECO:0000313|Proteomes:UP000001949}.
FT REGION 36..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 327 AA; 36216 MW; A18D8D9E9AD4C67C CRC64;
MLKRIRGGNT TITTAKSLDV TAVNQLNTEP LVRNRKRTRA TQTHTHTNTH TSLNSLNSVN
STNTSNIVNS VNSLNSVNSV GSVRLGKSLK PIPNTKTTLN TLNTGKINTN TVNTGKINTN
TLNTGKINTN TLNTVNTGVG KEGEVLSRIN SIISKSRFKR LCREYVGDFW SRVDSNEIPI
LPLLHIANSC STGGTVETVE NTVEGTVGAV EASAENVEAG TSGPSAVTEI QNISIITMSV
SDYSYKSTPF GDVYYSPRFQ DDKYIYRYVI LTKGVRNEAY RLLKQSKSYL LTEHQIIREL
CIDLSPGWEH FMLFKNRLDE LILRRKL
//
