ID Q4N317_THEPA Unreviewed; 346 AA.
AC Q4N317;
DT 02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 02-AUG-2005, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=Meiotic recombination protein DMC1, putative {ECO:0000313|EMBL:EAN31522.1};
GN OrderedLocusNames=TP04_0170 {ECO:0000313|EMBL:EAN31522.1};
OS Theileria parva (East coast fever infection agent).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=5875 {ECO:0000313|EMBL:EAN31522.1, ECO:0000313|Proteomes:UP000001949};
RN [1] {ECO:0000313|EMBL:EAN31522.1, ECO:0000313|Proteomes:UP000001949}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Muguga {ECO:0000313|EMBL:EAN31522.1,
RC ECO:0000313|Proteomes:UP000001949};
RX PubMed=15994558; DOI=10.1126/science.1110439;
RA Gardner M.J., Bishop R., Shah T., de Villiers E.P., Carlton J.M., Hall N.,
RA Ren Q., Paulsen I.T., Pain A., Berriman M., Wilson R.J.M., Sato S.,
RA Ralph S.A., Mann D.J., Xiong Z., Shallom S.J., Weidman J., Jiang L.,
RA Lynn J., Weaver B., Shoaibi A., Domingo A.R., Wasawo D., Crabtree J.,
RA Wortman J.R., Haas B., Angiuoli S.V., Creasy T.H., Lu C., Suh B.,
RA Silva J.C., Utterback T.R., Feldblyum T.V., Pertea M., Allen J.,
RA Nierman W.C., Taracha E.L.N., Salzberg S.L., White O.R., Fitzhugh H.A.,
RA Morzaria S., Venter J.C., Fraser C.M., Nene V.;
RT "Genome sequence of Theileria parva, a bovine pathogen that transforms
RT lymphocytes.";
RL Science 309:134-137(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RecA family. DMC1 subfamily.
CC {ECO:0000256|ARBA:ARBA00008897}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN31522.1}.
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DR EMBL; AAGK01000004; EAN31522.1; -; Genomic_DNA.
DR RefSeq; XP_763805.1; XM_758712.1.
DR AlphaFoldDB; Q4N317; -.
DR STRING; 5875.Q4N317; -.
DR EnsemblProtists; EAN31522; EAN31522; TP04_0170.
DR GeneID; 3501316; -.
DR KEGG; tpv:TP04_0170; -.
DR VEuPathDB; PiroplasmaDB:TpMuguga_04g00170; -.
DR eggNOG; KOG1434; Eukaryota.
DR InParanoid; Q4N317; -.
DR OMA; REATYVI; -.
DR Proteomes; UP000001949; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0007131; P:reciprocal meiotic recombination; IEA:InterPro.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011940; Dmc1.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR016467; DNA_recomb/repair_RecA-like.
DR InterPro; IPR010995; DNA_repair_Rad51/TF_NusA_a-hlx.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR NCBIfam; TIGR02238; recomb_DMC1; 1.
DR PANTHER; PTHR22942:SF30; MEIOTIC RECOMBINATION PROTEIN DMC1_LIM15 HOMOLOG; 1.
DR PANTHER; PTHR22942; RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; 1.
DR Pfam; PF08423; Rad51; 1.
DR PIRSF; PIRSF005856; Rad51; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47794; Rad51 N-terminal domain-like; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003422};
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003422};
KW Reference proteome {ECO:0000313|Proteomes:UP000001949}.
FT DOMAIN 107..276
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT DOMAIN 283..346
FT /note="RecA family profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50163"
SQ SEQUENCE 346 AA; 38431 MW; A6309F5E5BE66905 CRC64;
MVTVPVTKSK GVSIQSSTNE DISDTILKPF QPIERLEELG INVTDINKLK AAGICTVLGV
IQTTKKDLCN IKGLTELKVD KISDCASKLE VTNSFISASE LYKIRKSILK INTGSEMLNR
LLNGGIETMS ITELFGENRT GKTQICHTIS VTSQIINPTE PFKVCYIDTE NTFRPEKIEK
ICERFDLDPM ITLDNILYSK AYTNEHLLQL ISNITSKMVE ERFVLLIIDS IMSLFRVDYS
GRGELAERQQ RLNKLLSNLL KIAQQFNVAI VLTNHVISEP SGALSFISNP IKPAGGNVIG
HASTCRLSLR KGKGNQRICK VYDSPNLPES ECIFELSDSG IIDVTE
//
