GenomeNet

Database: UniProt
Entry: Q4P733
LinkDB: Q4P733
Original site: Q4P733 
ID   DED1_USTMA              Reviewed;         672 AA.
AC   Q4P733; A0A0D1CN17;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   16-OCT-2019, entry version 93.
DE   RecName: Full=ATP-dependent RNA helicase DED1;
DE            EC=3.6.4.13;
GN   Name=DED1; ORFNames=UMAG_04080;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T.,
RA   Saville B.J., Banuett F., Kronstad J.W., Gold S.E., Mueller O.,
RA   Perlin M.H., Woesten H.A.B., de Vries R., Ruiz-Herrera J.,
RA   Reynaga-Pena C.G., Snetselaar K., McCann M., Perez-Martin J.,
RA   Feldbruegge M., Basse C.W., Steinberg G., Ibeas J.I., Holloman W.,
RA   Guzman P., Farman M.L., Stajich J.E., Sentandreu R.,
RA   Gonzalez-Prieto J.M., Kennell J.C., Molina L., Schirawski J.,
RA   Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N., Scherer M.,
RA   Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B., Meng S.,
RA   Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U.,
RA   Muensterkoetter M., Haase D., Oesterheld M., Mewes H.-W.,
RA   Mauceli E.W., DeCaprio D., Wade C.M., Butler J., Young S.K.,
RA   Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen
RT   Ustilago maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G.,
RA   Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: ATP-binding RNA helicase involved in translation
CC       initiation. Remodels RNA in response to ADP and ATP concentrations
CC       by facilitating disruption, but also formation of RNA duplexes (By
CC       similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- DOMAIN: The Q motif is unique to and characteristic of the DEAD
CC       box family of RNA helicases and controls ATP binding and
CC       hydrolysis.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX3/DED1
CC       subfamily. {ECO:0000305}.
DR   EMBL; CM003150; KIS68038.1; -; Genomic_DNA.
DR   RefSeq; XP_011390514.1; XM_011392212.1.
DR   SMR; Q4P733; -.
DR   STRING; 5270.UM04080P0; -.
DR   PRIDE; Q4P733; -.
DR   EnsemblFungi; KIS68038; KIS68038; UMAG_04080.
DR   GeneID; 23564361; -.
DR   KEGG; uma:UMAG_04080; -.
DR   EuPathDB; FungiDB:UMAG_04080; -.
DR   HOGENOM; HOG000268804; -.
DR   InParanoid; Q4P733; -.
DR   KO; K11594; -.
DR   OMA; CYRSWVR; -.
DR   OrthoDB; 595675at2759; -.
DR   Proteomes; UP000000561; Chromosome 11.
DR   Proteomes; UP000000561; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0043186; C:P granule; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Helicase; Hydrolase;
KW   Initiation factor; Nucleotide-binding; Protein biosynthesis;
KW   Reference proteome; RNA-binding.
FT   CHAIN         1    672       ATP-dependent RNA helicase DED1.
FT                                /FTId=PRO_0000232162.
FT   DOMAIN      220    412       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      423    584       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND     233    240       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   MOTIF       189    217       Q motif.
FT   MOTIF       356    359       DEAD box.
SQ   SEQUENCE   672 AA;  71337 MW;  F047898AE9A0FA9C CRC64;
     MTYENNTHQQ NGAGTADIES RFANMSVQNG AAGGAPRKAY VPPHLRSQQQ PASLNSSAAS
     FSPRAPAAFN GNGNSNGNGN GPAAPAAPAA FQSFNRGAPR GGAGGWDAPS SGGYGGARNG
     GGYGGGARND GFGQWKDGKH VPGPHNPRLQ KELFGEEGDG LHQSMGINFD KYGDIPVEAT
     GRDVPEPVTT FTSPPIDAHL LENIKLARYT NPTPVQKYSI PIIKLGRDLM GCAQTGSGKT
     GGFLFPILSA LFTHGPPPPS AAEMAQGGYN RRKAYPSTLI LAPTRELVSQ IHDEARKFTY
     RSWVKPAVVY GGADIVTQLR QIERGCDLLS ATPGRLVDLM ERGRISLSNV RFLVLDEADR
     MLDMGFEPQI RRIVEGEDMP GVMDRQTLMF SATFPRDIQL LAKDFLKEYV FLSVGRVGST
     SENITQKIEY VEDDDKRSVL LDVLASMPSG GLTLIFVETK RMADMLSDFL LRSKIGATSI
     HGDRTQRERE RALELFRSGK TPIMVATAVA ARGLDIPNVT HVVNYDLPSD VDDYVHRIGR
     TGRAGNVGHA TAFFNRGNKN IVRDLIELLK EANQEVPQWL EAVARESMFG AGGGSRGGRG
     RGRGRGGASS FGNRDARTMN GPSSGGGRGF GGGYGGGMGG GLGGSYGAGA AAYGGPPPAS
     NGGSYGGNSS WW
//
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