ID Q4PT31_ARATH Unreviewed; 380 AA.
AC Q4PT31;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 132.
DE SubName: Full=Disease resistance protein (TIR-NBS class) {ECO:0000313|EMBL:AEE29614.1};
DE SubName: Full=Putative disease resistance protein {ECO:0000313|EMBL:AAY78612.1};
GN Name=TN2 {ECO:0000313|TAIR:AT1G17615};
GN OrderedLocusNames=At1g17615 {ECO:0000313|Araport:AT1G17615,
GN ECO:0000313|EMBL:AEE29614.1};
GN ORFNames=F1L3.31 {ECO:0000313|EMBL:AEE29614.1}, F1L3_31
GN {ECO:0000313|EMBL:AEE29614.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AAY78612.1};
RN [1] {ECO:0000313|EMBL:AEE29614.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|EMBL:AAY78612.1}
RP NUCLEOTIDE SEQUENCE.
RA Underwood B.A., Xiao Y., Moskal W., Monaghan E., Wang W., Redman J.,
RA Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AEE29614.1}
RP NUCLEOTIDE SEQUENCE.
RG TAIR;
RA Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AEE29614.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
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DR EMBL; DQ056455; AAY78612.1; -; mRNA.
DR EMBL; CP002684; AEE29614.1; -; Genomic_DNA.
DR RefSeq; NP_173205.1; NM_101624.2.
DR AlphaFoldDB; Q4PT31; -.
DR SMR; Q4PT31; -.
DR PaxDb; 3702-AT1G17615-1; -.
DR EnsemblPlants; AT1G17615.1; AT1G17615.1; AT1G17615.
DR GeneID; 838338; -.
DR Gramene; AT1G17615.1; AT1G17615.1; AT1G17615.
DR KEGG; ath:AT1G17615; -.
DR Araport; AT1G17615; -.
DR TAIR; AT1G17615; TN2.
DR HOGENOM; CLU_001561_2_3_1; -.
DR OMA; QSHCFLE; -.
DR OrthoDB; 1211301at2759; -.
DR PRO; PR:Q4PT31; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q4PT31; baseline and differential.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0042742; P:defense response to bacterium; IGI:TAIR.
DR GO; GO:0050832; P:defense response to fungus; IGI:TAIR.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11017:SF207; DISEASE RESISTANCE PROTEIN (TIR-NBS CLASS)-RELATED; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000006548}.
FT DOMAIN 13..178
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 380 AA; 43241 MW; DA01ADCC3B1C545D CRC64;
MYSSSSSSSA TPQKFDVFLS FRGKDTRRTF ISFLYKELIE MGIRTFKDDV ELQSGRRIAS
DLLAAIENSK IAVVIISKNY SASPWCLQEL VMIMDVEKKG SIIVMPIFYN VEPAHVRRQI
EQVAKQFRKH EGRENYETVV SWRQALTNLA SISGHCSRDC EDDSKLLDEI TKRISDMLFS
VTPPSESINN QLGFDARMKE LYPLLDLDSN EGVRVVGIWA RGGNGRSALA RYVYQKIFKK
FQSHCFLENV KGIPHDCQMS NLRDEFLIRI QGGYSRMKTS GLIKKRLMSQ KVLLVANNVD
KLEQLDALAE YFNCFGPGSI VLITTQDKQL LVAFGIKVVY EVECLRCFEV RQLFRQIGFR
ERDLNVGSEL SSPISGTESS
//
