ID Q4Q0E9_LEIMA Unreviewed; 165 AA.
AC Q4Q0E9;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Putative centrin {ECO:0000313|EMBL:CAJ09586.1};
GN ORFNames=LMJF_36_6110 {ECO:0000313|EMBL:CAJ09586.1};
OS Leishmania major.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5664 {ECO:0000313|EMBL:CAJ09586.1, ECO:0000313|Proteomes:UP000000542};
RN [1] {ECO:0000313|EMBL:CAJ09586.1, ECO:0000313|Proteomes:UP000000542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/IL/81/Friedlin {ECO:0000313|Proteomes:UP000000542};
RX PubMed=16020728; DOI=10.1126/science.1112680;
RA Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G.,
RA Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A.,
RA Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M.,
RA Bianchettin G., Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E.,
RA Ciarloni L., Clayton C., Coulson R.M., Cronin A., Cruz A.K., Davies R.M.,
RA De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N.,
RA Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A.,
RA Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S.,
RA Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M.,
RA Masuy D., Matthews K., Michaeli S., Mottram J.C., Muller-Auer S.,
RA Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M.,
RA Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E.,
RA Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C.,
RA Rutter S., Saunders D., Schafer M., Schein J., Schwartz D.C., Seeger K.,
RA Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V.,
RA Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J.,
RA Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D.,
RA Barrell B., Myler P.J.;
RT "The genome of the kinetoplastid parasite, Leishmania major.";
RL Science 309:436-442(2005).
RN [2] {ECO:0000313|EMBL:CAJ09586.1, ECO:0000313|Proteomes:UP000000542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/IL/81/Friedlin {ECO:0000313|Proteomes:UP000000542};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
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DR EMBL; FR796432; CAJ09586.1; -; Genomic_DNA.
DR RefSeq; XP_001687199.1; XM_001687147.1.
DR AlphaFoldDB; Q4Q0E9; -.
DR STRING; 5664.Q4Q0E9; -.
DR EnsemblProtists; CAJ09586; CAJ09586; LMJF_36_6110.
DR GeneID; 5655916; -.
DR KEGG; lma:LMJF_36_6110; -.
DR VEuPathDB; TriTrypDB:LmjF.36.6110; -.
DR VEuPathDB; TriTrypDB:LMJFC_360079800; -.
DR VEuPathDB; TriTrypDB:LMJLV39_360073900; -.
DR VEuPathDB; TriTrypDB:LMJSD75_360073900; -.
DR eggNOG; KOG0028; Eukaryota.
DR HOGENOM; CLU_061288_18_2_1; -.
DR InParanoid; Q4Q0E9; -.
DR OMA; QEIIREC; -.
DR Proteomes; UP000000542; Chromosome 36.
DR GO; GO:0005930; C:axoneme; ISO:GeneDB.
DR GO; GO:0005929; C:cilium; ISO:GeneDB.
DR GO; GO:0005737; C:cytoplasm; ISO:GeneDB.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0060285; P:cilium-dependent cell motility; ISO:GeneDB.
DR GO; GO:0036159; P:inner dynein arm assembly; ISO:GeneDB.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23050:SF23; AT22559P; 1.
DR PANTHER; PTHR23050; CALCIUM BINDING PROTEIN; 1.
DR Pfam; PF13499; EF-hand_7; 2.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000542};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 21..56
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 131..165
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 165 AA; 18800 MW; AE282AF96C00FC3B CRC64;
MLNTAFSTAD GRRLPRDLTD QQKRDIEEAF RVLDVKGVST ITPNDLKVAL RALGYEPDKD
AVRKLVAEMD RGGVSSNLVL SEFEDVMRQR FFAEDKDDEV DLAFPLFTEG KSEFISLDDL
KRVAAEVGED IPEDVLQEII RECDVLDRDG RISREEFNKM LKSDK
//
