ID Q4Q7C7_LEIMA Unreviewed; 449 AA.
AC Q4Q7C7;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAJ06296.1};
GN ORFNames=LMJF_30_1670 {ECO:0000313|EMBL:CAJ06296.1};
OS Leishmania major.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5664 {ECO:0000313|EMBL:CAJ06296.1, ECO:0000313|Proteomes:UP000000542};
RN [1] {ECO:0000313|EMBL:CAJ06296.1, ECO:0000313|Proteomes:UP000000542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/IL/81/Friedlin {ECO:0000313|Proteomes:UP000000542};
RX PubMed=16020728; DOI=10.1126/science.1112680;
RA Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G.,
RA Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A.,
RA Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M.,
RA Bianchettin G., Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E.,
RA Ciarloni L., Clayton C., Coulson R.M., Cronin A., Cruz A.K., Davies R.M.,
RA De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N.,
RA Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A.,
RA Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S.,
RA Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M.,
RA Masuy D., Matthews K., Michaeli S., Mottram J.C., Muller-Auer S.,
RA Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M.,
RA Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E.,
RA Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C.,
RA Rutter S., Saunders D., Schafer M., Schein J., Schwartz D.C., Seeger K.,
RA Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V.,
RA Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J.,
RA Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D.,
RA Barrell B., Myler P.J.;
RT "The genome of the kinetoplastid parasite, Leishmania major.";
RL Science 309:436-442(2005).
RN [2] {ECO:0000313|EMBL:CAJ06296.1, ECO:0000313|Proteomes:UP000000542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/IL/81/Friedlin {ECO:0000313|Proteomes:UP000000542};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
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DR EMBL; FR796426; CAJ06296.1; -; Genomic_DNA.
DR RefSeq; XP_001684771.1; XM_001684719.1.
DR AlphaFoldDB; Q4Q7C7; -.
DR EnsemblProtists; CAJ06296; CAJ06296; LMJF_30_1670.
DR GeneID; 5653710; -.
DR KEGG; lma:LMJF_30_1670; -.
DR VEuPathDB; TriTrypDB:LmjF.30.1670; -.
DR VEuPathDB; TriTrypDB:LMJFC_300026000; -.
DR VEuPathDB; TriTrypDB:LMJLV39_300023100; -.
DR VEuPathDB; TriTrypDB:LMJSD75_300022800; -.
DR eggNOG; ENOG502RZ13; Eukaryota.
DR HOGENOM; CLU_610392_0_0_1; -.
DR InParanoid; Q4Q7C7; -.
DR OMA; HTACQHI; -.
DR Proteomes; UP000000542; Chromosome 30.
DR GO; GO:0005737; C:cytoplasm; ISO:GeneDB.
DR GO; GO:0044183; F:protein folding chaperone; IBA:GO_Central.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0042026; P:protein refolding; IBA:GO_Central.
DR Gene3D; 3.90.1280.10; HSP33 redox switch-like; 1.
DR InterPro; IPR000397; Heat_shock_Hsp33.
DR InterPro; IPR016154; Heat_shock_Hsp33_C.
DR InterPro; IPR016153; Heat_shock_Hsp33_N.
DR PANTHER; PTHR30111; 33 KDA CHAPERONIN; 1.
DR PANTHER; PTHR30111:SF1; 33 KDA CHAPERONIN; 1.
DR Pfam; PF01430; HSP33; 1.
DR SUPFAM; SSF64397; Hsp33 domain; 1.
DR SUPFAM; SSF118352; HSP33 redox switch-like; 1.
PE 4: Predicted;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Redox-active center {ECO:0000256|ARBA:ARBA00023284};
KW Reference proteome {ECO:0000313|Proteomes:UP000000542};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
SQ SEQUENCE 449 AA; 48973 MW; 40AF1D8E93100944 CRC64;
MHAFRTRDIT LRVPSKDKLL RFSFCSSRHL LAETIRRHDL LRSTGAHVDF LQLLGTQITF
TSLLASALEG EERVEARFTA EEATILTEAL ALGECRCYLR PEYNAQLAEC GLPTFPLRVN
RILYRQEKPF SSVVHADLAE LLQPPCDVAS SFAAASSGAN EASGAPFSLY LPDMERRVPL
EAWKSFFSYN SSLHAYNYLR RSDGSVPAVW LQSRIDAVRL VDHGFLNVDS TAAAAAWQRG
EACSDEDDEK AQDIRRALLH AIPFSFGVVV TPLAAGVAVD QRVNQLNRVV MEAAALLSAP
SGGGATVTSA LQPLLDRCAE KHTACQHILS LVSGDHDGAY QAAVAARQYN DDPAQVAAVV
DPIRRALGVQ DFVVPLAATE AARSGLDFFC RCSKQNVLES LVSAPPRALE SLKGSDNTVH
CSFCGRRYKL AGAEWQELEM ARSASTPPQ
//
