ID Q4QDL4_LEIMA Unreviewed; 466 AA.
AC Q4QDL4;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Putative peroxin 13 {ECO:0000313|EMBL:CAJ07092.1};
GN Name=PEX13 {ECO:0000313|EMBL:CAJ07092.1};
GN ORFNames=LMJF_19_0070 {ECO:0000313|EMBL:CAJ07092.1};
OS Leishmania major.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5664 {ECO:0000313|EMBL:CAJ07092.1, ECO:0000313|Proteomes:UP000000542};
RN [1] {ECO:0000313|EMBL:CAJ07092.1, ECO:0000313|Proteomes:UP000000542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/IL/81/Friedlin {ECO:0000313|Proteomes:UP000000542};
RX PubMed=16020728; DOI=10.1126/science.1112680;
RA Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G.,
RA Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A.,
RA Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M.,
RA Bianchettin G., Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E.,
RA Ciarloni L., Clayton C., Coulson R.M., Cronin A., Cruz A.K., Davies R.M.,
RA De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N.,
RA Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A.,
RA Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S.,
RA Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M.,
RA Masuy D., Matthews K., Michaeli S., Mottram J.C., Muller-Auer S.,
RA Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M.,
RA Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E.,
RA Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C.,
RA Rutter S., Saunders D., Schafer M., Schein J., Schwartz D.C., Seeger K.,
RA Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V.,
RA Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J.,
RA Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D.,
RA Barrell B., Myler P.J.;
RT "The genome of the kinetoplastid parasite, Leishmania major.";
RL Science 309:436-442(2005).
RN [2] {ECO:0000313|EMBL:CAJ07092.1, ECO:0000313|Proteomes:UP000000542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/IL/81/Friedlin {ECO:0000313|Proteomes:UP000000542};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
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DR EMBL; FR796415; CAJ07092.1; -; Genomic_DNA.
DR RefSeq; XP_001682584.1; XM_001682532.1.
DR AlphaFoldDB; Q4QDL4; -.
DR STRING; 5664.Q4QDL4; -.
DR TCDB; 3.A.20.1.4; the peroxisomal protein importer (ppi) family.
DR EnsemblProtists; CAJ07092; CAJ07092; LMJF_19_0070.
DR GeneID; 5651111; -.
DR KEGG; lma:LMJF_19_0070; -.
DR VEuPathDB; TriTrypDB:LmjF.19.0070; -.
DR VEuPathDB; TriTrypDB:LMJFC_190005800; -.
DR VEuPathDB; TriTrypDB:LMJLV39_190005600; -.
DR VEuPathDB; TriTrypDB:LMJSD75_190005500; -.
DR eggNOG; ENOG502S2KK; Eukaryota.
DR HOGENOM; CLU_706971_0_0_1; -.
DR InParanoid; Q4QDL4; -.
DR OMA; CFGTYYS; -.
DR Proteomes; UP000000542; Chromosome 19.
DR GO; GO:0046860; C:glycosome membrane; ISO:GeneDB.
DR GO; GO:0005794; C:Golgi apparatus; ISO:GeneDB.
DR GO; GO:0015919; P:peroxisomal membrane transport; ISO:GeneDB.
DR GO; GO:0007031; P:peroxisome organization; ISO:GeneDB.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000542};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 393..462
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 160..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 466 AA; 50023 MW; F2BA0D824DCF9890 CRC64;
MISLRRSSSL LVEEWKSIVA PVCYASLEFF VVSSTFSLIR PFIMFSGMYG GGLGGMGSAM
YGGGLGGMGG MYGGGLGGMS GMYGNSGLMG GSSYAMSGGL NSFVRNNPYG SNSNYSVGGF
NSLGSNADGT QNNGMQSSIN LQQQADQSNH LASPIHQHAA TLPPLNESPE ERSRRIQAEH
KKERQLIRQQ REQHRQARLQ ARMEIVGHLT NVLVQGLRSA MELFGVCFGT YYSMKAVRAF
SSAQERMPSM GMGMGANYPY GAAVAKTQAV ATGASGVQQV AKAASGGSSK WRAWLLCIAF
FLLGEVVYGI ATRQRAKLPQ RRRRITGPAE DAYGNVLSQD EYEVSIRSSD AESRLTEGDK
GEEETLSEAW GQAYNANGVC GVSQAARPSG GNGTRRVYYA LYDYQAPQAD GSCLSFKAGD
EFVVENYAEG SWCEAMAVEG GSYSSHGRRG LVPSNFLRLA ERITKL
//
