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Database: UniProt
Entry: Q4RWI3_TETNG
LinkDB: Q4RWI3_TETNG
Original site: Q4RWI3_TETNG 
ID   Q4RWI3_TETNG            Unreviewed;       515 AA.
AC   Q4RWI3;
DT   19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   19-JUL-2005, sequence version 1.
DT   16-OCT-2019, entry version 100.
DE   SubName: Full=Chromosome 3 SCAF14987, whole genome shotgun sequence {ECO:0000313|EMBL:CAG07249.1};
DE   SubName: Full=Potassium voltage-gated channel subfamily J member 19a {ECO:0000313|Ensembl:ENSTNIP00000017993};
GN   ORFNames=GSTENG00027847001 {ECO:0000313|EMBL:CAG07249.1};
OS   Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS   nigroviridis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Tetraodon.
OX   NCBI_TaxID=99883 {ECO:0000313|EMBL:CAG07249.1};
RN   [1] {ECO:0000313|EMBL:CAG07249.1, ECO:0000313|Ensembl:ENSTNIP00000017993}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15496914; DOI=10.1038/nature03025;
RA   Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA   Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A.,
RA   Nicaud S., Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B.,
RA   Dasilva C., Salanoubat M., Levy M., Boudet N., Castellano S.,
RA   Anthouard V., Jubin C., Castelli V., Katinka M., Vacherie B.,
RA   Biemont C., Skalli Z., Cattolico L., Poulain J., De Berardinis V.,
RA   Cruaud C., Duprat S., Brottier P., Coutanceau J.-P., Gouzy J.,
RA   Parra G., Lardier G., Chapple C., McKernan K.J., McEwan P., Bosak S.,
RA   Kellis M., Volff J.-N., Guigo R., Zody M.C., Mesirov J.,
RA   Lindblad-Toh K., Birren B., Nusbaum C., Kahn D., Robinson-Rechavi M.,
RA   Laudet V., Schachter V., Quetier F., Saurin W., Scarpelli C.,
RA   Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT   "Genome duplication in the teleost fish Tetraodon nigroviridis reveals
RT   the early vertebrate proto-karyotype.";
RL   Nature 431:946-957(2004).
RN   [2] {ECO:0000313|EMBL:CAG07249.1}
RP   NUCLEOTIDE SEQUENCE.
RG   Genoscope;
RG   Whitehead Institute Centre for Genome Research;
RL   Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSTNIP00000017993}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; CAAE01014987; CAG07249.1; -; Genomic_DNA.
DR   Ensembl; ENSTNIT00000018217; ENSTNIP00000017993; ENSTNIG00000014946.
DR   KEGG; tng:GSTEN00027847G001; -.
DR   eggNOG; KOG3827; Eukaryota.
DR   eggNOG; ENOG410XQ62; LUCA.
DR   GeneTree; ENSGT00970000193368; -.
DR   OMA; FSVDCIN; -.
DR   TreeFam; TF313676; -.
DR   Proteomes; UP000007303; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015467; F:G-protein activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003274; K_chnl_inward-rec_Kir3.1.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01327; KIR31CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007303};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     72     93       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    147    170       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       35    175       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      182    353       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      342    362       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      387    410       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   515 AA;  57996 MW;  190B5F7CD73BBA37 CRC64;
     MAALRRKFGE DYQVVNTNRP TPFSAPVKKK RQRFVDKNGR CNVQHGNLGG ETSRYLSDLF
     TTLVDLKWRW NLLIFILTYT IAWLVMASMW WIIAYIRGDL NHGHDQDYTP CVANVYNFPS
     AFLFFIETEA TIGYGHRYIT EKCPEGIILF LFQSLLGSIV DAFLIGCMFI KMSQPKKRAE
     TLMFSQDAVI SQRDGKLCLM FRVGNLRNSH MVSAQIRCKL IKSRQTPEGE FLPLDQCELD
     VGFGTGADQL FLVSPLTICH EINPKSPFFD LSKRSLMNEQ FEIVVILEGI VETTGMTCQA
     RTSYTEDEVL WGHRFLPVMS LEEGFFRVDY SQFHSTFEVP TPPHSVKEHA EKNSLPSPLS
     TPVPALPECH AARRDRVFSV DCISTEEERG HQGGTGGRLP SKLQRMSSSG KEDLQRKVLL
     LSSQHSEKAC STGDLPLKLQ RLSSSSGPEA ENRLQLKSLK VGFEPMTQST GDLYQHSLAP
     TLAPAPAPMY SPLLSGAGRL EDKLPAKLRK MNADR
//
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