ID Q4SHT5_TETNG Unreviewed; 374 AA.
AC Q4SHT5;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE RecName: Full=Serine protease 23 {ECO:0000256|ARBA:ARBA00040551};
GN Name=PRSS23 {ECO:0000313|Ensembl:ENSTNIP00000012356.1};
GN ORFNames=GSTENG00018013001 {ECO:0000313|EMBL:CAF99797.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|EMBL:CAF99797.1};
RN [1] {ECO:0000313|EMBL:CAF99797.1, ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|EMBL:CAF99797.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope;
RG Whitehead Institute Centre for Genome Research;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSTNIP00000012356.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase S1 family.
CC {ECO:0000256|ARBA:ARBA00007664}.
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DR EMBL; CAAE01014581; CAF99797.1; -; Genomic_DNA.
DR Ensembl; ENSTNIT00000012547.1; ENSTNIP00000012356.1; ENSTNIG00000009483.1.
DR KEGG; tng:GSTEN00018013G001; -.
DR GeneTree; ENSGT00390000000155; -.
DR HOGENOM; CLU_055829_0_0_1; -.
DR OMA; WIKGNFM; -.
DR TreeFam; TF329011; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR PANTHER; PTHR15462; SERINE PROTEASE; 1.
DR PANTHER; PTHR15462:SF10; SERINE PROTEASE 23; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 113..364
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|SMART:SM00020"
FT REGION 83..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAF99797.1"
SQ SEQUENCE 374 AA; 42466 MW; 48B7C80E53E4FD5F CRC64;
PQWVLQRVPV VLPQQTQVKP APQFLSEARL DVSSSCDPEC HKKAPRPSYQ DLREFLAYET
LHSNGQLTET AVGIYSFRTP SNTHSAYSSE SPGKQAQPHV RRKRQIFGHD SRFSIAGQDF
LLKYPFSVSV KLSTGCSGTL VGDRHVLTAA HCVHDGKNYV KGAKKLRVGF LKPKQRDTPL
SPFYSPSNFI NRVGGGPTPY VPPTNSKMKF QWIRAKRTHI PKGWIKGNAN EIGMDYDYAL
LELKKPHKRQ HMKLGISPPA QRLPGRRVHF SGFDNDRPGQ LVYRFCRAGE ETSDLLYQHC
DAQPGASGSG VYARMWDRRR QRWERKVIGV FSGHQWVERQ GASQEFNVAV RVTPLKYAQI
CYWIKGNFVD CREG
//
