ID Q4SU55_TETNG Unreviewed; 506 AA.
AC Q4SU55;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE RecName: Full=peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277};
DE EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};
DE Flags: Fragment;
GN ORFNames=GSTENG00012623001 {ECO:0000313|EMBL:CAF95827.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|EMBL:CAF95827.1};
RN [1] {ECO:0000313|EMBL:CAF95827.1, ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|EMBL:CAF95827.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope;
RG Whitehead Institute Centre for Genome Research;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSTNIP00000009396.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8; Evidence={ECO:0000256|PROSITE-
CC ProRule:PRU00277};
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DR EMBL; CAAE01014024; CAF95827.1; -; Genomic_DNA.
DR STRING; 99883.ENSTNIP00000009396; -.
DR Ensembl; ENSTNIT00000009567.1; ENSTNIP00000009396.1; ENSTNIG00000006619.1.
DR KEGG; tng:GSTEN00012623G001; -.
DR GeneTree; ENSGT00940000156331; -.
DR OMA; YDRHTLV; -.
DR TreeFam; TF105296; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.10.50.40; -; 4.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR001179; PPIase_FKBP_dom.
DR PANTHER; PTHR46046:SF3; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP10; 1.
DR PANTHER; PTHR46046; PEPTIDYLPROLYL ISOMERASE; 1.
DR Pfam; PF00254; FKBP_C; 4.
DR SUPFAM; SSF54534; FKBP-like; 4.
DR PROSITE; PS50059; FKBP_PPIASE; 4.
PE 4: Predicted;
KW Isomerase {ECO:0000256|PROSITE-ProRule:PRU00277};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Rotamase {ECO:0000256|PROSITE-ProRule:PRU00277};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..506
FT /note="peptidylprolyl isomerase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014105093"
FT DOMAIN 47..135
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT DOMAIN 159..247
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT DOMAIN 271..359
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT DOMAIN 383..470
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT NON_TER 506
FT /evidence="ECO:0000313|EMBL:CAF95827.1"
SQ SEQUENCE 506 AA; 55826 MW; 895F0D49B4C27EE1 CRC64;
MFLCYVVFFL LTSGSSSVEG NPSPVLGDVV VDRYFIPKIC VRESKSGDHI RYHYNATFAD
GKTFDSSHQR GDAKVALLGE GRLLEGIDRG LRGMCVNERR SITVPPHLGY GSTGAGKVVP
PDSTLVFDIH LLDVWNQADL VVTKTVTTPK DCKRSVMRTD FVRYHFNGTL LDGTVFDSSY
TRKQTHNTLV GEGWLVKGMD EGLLGMCVGE IRNIVIPPFK AYGEKGSGSE IPPQATLVFD
VLLVDLHNPK DNITVEELVV PDTCTRRTVA GDYIRYHYNG TFLNGVTFDT SYQRNSTYNT
YIGMGYVIPG VDQALLGLCT GQKRRVTIPP RLAYGENGAG DVIPPSAVLV FDIHVIDFHN
PNDTVDIRTT YRPESCNETT KENDLVRYHY NCTLVDGTLL FSSHDDDNLQ SVVLGTDKVI
DGLDLALRGM CVEEKRLVTV PPHLGHGENG ATGVPGSAVL VFDIELVSFE KGVPPGYLFV
WLQENPPNLF EALDINSNKE VPQEEV
//
