ID   Q4U9H0_THEAN            Unreviewed;      1089 AA.
AC   Q4U9H0;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   27-MAR-2024, entry version 89.
DE   RecName: Full=Structural maintenance of chromosomes protein 5 {ECO:0000256|ARBA:ARBA00018687};
GN   ORFNames=TA08750 {ECO:0000313|EMBL:CAI76533.1};
OS   Theileria annulata.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC   Theileriidae; Theileria.
OX   NCBI_TaxID=5874 {ECO:0000313|EMBL:CAI76533.1, ECO:0000313|Proteomes:UP000001950};
RN   [1] {ECO:0000313|EMBL:CAI76533.1, ECO:0000313|Proteomes:UP000001950}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ankara {ECO:0000313|Proteomes:UP000001950};
RX   PubMed=15994557; DOI=10.1126/science.1110418;
RA   Pain A., Renauld H., Berriman M., Murphy L., Yeats C.A., Weir W.,
RA   Kerhornou A., Aslett M., Bishop R., Bouchier C., Cochet M., Coulson R.M.R.,
RA   Cronin A., de Villiers E.P., Fraser A., Fosker N., Gardner M., Goble A.,
RA   Griffiths-Jones S., Harris D.E., Katzer F., Larke N., Lord A., Maser P.,
RA   McKellar S., Mooney P., Morton F., Nene V., O'Neil S., Price C.,
RA   Quail M.A., Rabbinowitsch E., Rawlings N.D., Rutter S., Saunders D.,
RA   Seeger K., Shah T., Squares R., Squares S., Tivey A., Walker A.R.,
RA   Woodward J., Dobbelaere D.A.E., Langsley G., Rajandream M.A., McKeever D.,
RA   Shiels B., Tait A., Barrell B.G., Hall N.;
RT   "Genome of the host-cell transforming parasite Theileria annulata compared
RT   with T. parva.";
RL   Science 309:131-133(2005).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the SMC family. SMC5 subfamily.
CC       {ECO:0000256|ARBA:ARBA00010171}.
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DR   EMBL; CR940353; CAI76533.1; -; Genomic_DNA.
DR   RefSeq; XP_953158.1; XM_948065.1.
DR   AlphaFoldDB; Q4U9H0; -.
DR   STRING; 5874.Q4U9H0; -.
DR   GeneID; 3863183; -.
DR   KEGG; tan:TA08750; -.
DR   VEuPathDB; PiroplasmaDB:TA08750; -.
DR   eggNOG; KOG0979; Eukaryota.
DR   InParanoid; Q4U9H0; -.
DR   OMA; ERDDCEE; -.
DR   OrthoDB; 232016at2759; -.
DR   Proteomes; UP000001950; Chromosome 4.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030915; C:Smc5-Smc6 complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038729; Rad50/SbcC_AAA.
DR   InterPro; IPR027131; SMC5.
DR   PANTHER; PTHR45916; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR   PANTHER; PTHR45916:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR   Pfam; PF13476; AAA_23; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001950}.
FT   DOMAIN          9..229
FT                   /note="Rad50/SbcC-type AAA"
FT                   /evidence="ECO:0000259|Pfam:PF13476"
FT   COILED          370..397
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          649..690
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          778..812
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1089 AA;  124872 MW;  503FA0218747270C CRC64;
     MRNGSIRYIS MENWMAYTGP VVVHSTPGVN IIAASNGSGK SAIVCAIALS LGFDLSILSR
     ADNISSFVKR GCMNSTLKVG LADGDSSQGV VHIERRIFLA ANLPNEHSES NKANSSNQNS
     GHKQKIPVRN EWFLNGKPTN LSNIKSLHKR LNIQLDNLVT FLAQANVGKF AAMTQQQLFR
     STLEAIDFKL VDELDNLIDL SQNLKSKVFE SKLLQESLNA CNKKLSELKI ISDTLIKVKD
     ATLYMNIVKL KLNQNKLSNV KKAYETTRKR IGDTNNDIYS HEIKHKKLEA KYNKIKSGSK
     SLYDLAKNNI EHANKIMQQD NPSCISNSMN DSGLNEPVQK AFYDSLSMLN SFSNDIQRKE
     SRMQISEEGE QTLREKIQSL TEDINSLKSK LSDVDEIVSA IATNKIKEDS IRYNLKKFTS
     NSYDDPMKLQ FEALLKNLSY VKRDMIMRYN RYCEAKSIEP KKFIVNDIKV SGVLNCSIVE
     NLIWNYLDCI LLHSSEFDDN LKLIKDFKLP TVTAPERNNV MCKVTDKMKS YGVMSFVHEL
     VTASDLTIQV LSSLCDINEA FIVDEKTYNK IFFSNKNKSN PENLFSEFYK TMLQEISNQI
     GERVSEIKYF VGNKKHVHKH FYKSNYFMDT EMEISNKPKV IVDFSNFGKD SRNEEMMALE
     NELDEVRSKL YDLNKKLNEQ NELNKNTNRK LYTLTKQKLT LEKSLNAITA NDNQKISGRS
     WKHDLNKLKK SRLKHISNSI VDTAKTLMIR IQNASEMKNI LIEANESYDE YCSKVVEIDE
     MSNNVTISKN QLDELKSSLT LLQNTFKEQK ERIDLYTNVI NDVKQAINDS EQLFESDLFE
     ESTNNFNEVK KRFENKLINL SDSDLEKELI KAEEQVKKLE TDDFEEIQLI KMIQDERTQK
     DKLKQKIYDN RTEVNTATEE LNKRYGIWES NVKQLVTEID YKFGKYMEYI GDGSGGQVRL
     DVDIDNIQEA KMRILVKFDR EKDLLPLTTS YQSGGERGVT TMVYILSVQN LTNNPFFVID
     EINQGLDSHY ERNLMKLLLA SNNCEEDSQN PSTPQYFILT PQLISGYDLS KATLHFPLNG
     PGIEQNIEI
//