ID Q4UA75_THEAN Unreviewed; 369 AA.
AC Q4UA75;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=DNA repair (Rad51 homologue) protein, putative {ECO:0000313|EMBL:CAI76278.1};
GN ORFNames=TA07350 {ECO:0000313|EMBL:CAI76278.1}, TAT_000317700
GN {ECO:0000313|EMBL:SVP94175.1}, TAV_000317600
GN {ECO:0000313|EMBL:SVP94866.1};
OS Theileria annulata.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=5874 {ECO:0000313|EMBL:CAI76278.1, ECO:0000313|Proteomes:UP000001950};
RN [1] {ECO:0000313|EMBL:CAI76278.1, ECO:0000313|Proteomes:UP000001950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ankara {ECO:0000313|Proteomes:UP000001950}, and Ankara isolate
RC clone C9 {ECO:0000313|EMBL:CAI76278.1};
RX PubMed=15994557; DOI=10.1126/science.1110418;
RA Pain A., Renauld H., Berriman M., Murphy L., Yeats C.A., Weir W.,
RA Kerhornou A., Aslett M., Bishop R., Bouchier C., Cochet M., Coulson R.M.R.,
RA Cronin A., de Villiers E.P., Fraser A., Fosker N., Gardner M., Goble A.,
RA Griffiths-Jones S., Harris D.E., Katzer F., Larke N., Lord A., Maser P.,
RA McKellar S., Mooney P., Morton F., Nene V., O'Neil S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rawlings N.D., Rutter S., Saunders D.,
RA Seeger K., Shah T., Squares R., Squares S., Tivey A., Walker A.R.,
RA Woodward J., Dobbelaere D.A.E., Langsley G., Rajandream M.A., McKeever D.,
RA Shiels B., Tait A., Barrell B.G., Hall N.;
RT "Genome of the host-cell transforming parasite Theileria annulata compared
RT with T. parva.";
RL Science 309:131-133(2005).
RN [2] {ECO:0000313|EMBL:SVP94175.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Anand {ECO:0000313|EMBL:SVP94175.1};
RA Quirk P.G., Krulwich T.A.;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RecA family.
CC {ECO:0000256|RuleBase:RU003422}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR940353; CAI76278.1; -; Genomic_DNA.
DR EMBL; UIVT01000004; SVP94175.1; -; Genomic_DNA.
DR EMBL; UIVS01000004; SVP94866.1; -; Genomic_DNA.
DR RefSeq; XP_952902.1; XM_947809.1.
DR AlphaFoldDB; Q4UA75; -.
DR STRING; 5874.Q4UA75; -.
DR GeneID; 3862742; -.
DR KEGG; tan:TA07350; -.
DR VEuPathDB; PiroplasmaDB:TA07350; -.
DR eggNOG; KOG1433; Eukaryota.
DR InParanoid; Q4UA75; -.
DR OMA; IHVARAY; -.
DR OrthoDB; 5477610at2759; -.
DR Proteomes; UP000001950; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd19513; Rad51; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR016467; DNA_recomb/repair_RecA-like.
DR InterPro; IPR010995; DNA_repair_Rad51/TF_NusA_a-hlx.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR PANTHER; PTHR22942:SF39; DNA REPAIR PROTEIN RAD51 HOMOLOG 1; 1.
DR PANTHER; PTHR22942; RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; 1.
DR Pfam; PF08423; Rad51; 2.
DR PIRSF; PIRSF005856; Rad51; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47794; Rad51 N-terminal domain-like; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003422};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003422};
KW Reference proteome {ECO:0000313|Proteomes:UP000001950};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 278..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 101..272
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT DOMAIN 308..368
FT /note="RecA family profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50163"
SQ SEQUENCE 369 AA; 40692 MW; 60E4DB7D8A4536A8 CRC64;
MSSDELSLVK EENSMGVSES GSQNPQRLEC LLSKGLLQRD LDLLREAGYS TLECVAYAPQ
KNLLVIKGLS EQKVLKIKAA CRELCHLGFC SGQDYLEARG NLIKFTTGSS QLDKLLQGGV
ETGSITEIIG EFKTGKSQLC HTLAVTCQLP VEQSGGEGKC LWVDSEGTFR PERIVSIAKR
FGLSPSDCLD NVAYARAYNT DHQLELLVEA SAMMAQTRFA LLIVDSATSL YRSDYSGRGE
LASRQMHLCK FLRALQRIAD TFGVAVVITN QVVARVDAMS TFFGILLLYI IIYCYILINI
CKFYIDKFVG NDKLPVGGHI IAHASQTRLF LRQSKGESRI CKVYDSPVLP EGEAVFAITD
GGINDYHDR
//
