ID   Q4UA87_THEAN            Unreviewed;       959 AA.
AC   Q4UA87;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Importin beta/transportin, putative {ECO:0000313|EMBL:CAI76266.1};
GN   ORFNames=TA07280 {ECO:0000313|EMBL:CAI76266.1};
OS   Theileria annulata.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC   Theileriidae; Theileria.
OX   NCBI_TaxID=5874 {ECO:0000313|EMBL:CAI76266.1, ECO:0000313|Proteomes:UP000001950};
RN   [1] {ECO:0000313|EMBL:CAI76266.1, ECO:0000313|Proteomes:UP000001950}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ankara {ECO:0000313|Proteomes:UP000001950};
RX   PubMed=15994557; DOI=10.1126/science.1110418;
RA   Pain A., Renauld H., Berriman M., Murphy L., Yeats C.A., Weir W.,
RA   Kerhornou A., Aslett M., Bishop R., Bouchier C., Cochet M., Coulson R.M.R.,
RA   Cronin A., de Villiers E.P., Fraser A., Fosker N., Gardner M., Goble A.,
RA   Griffiths-Jones S., Harris D.E., Katzer F., Larke N., Lord A., Maser P.,
RA   McKellar S., Mooney P., Morton F., Nene V., O'Neil S., Price C.,
RA   Quail M.A., Rabbinowitsch E., Rawlings N.D., Rutter S., Saunders D.,
RA   Seeger K., Shah T., Squares R., Squares S., Tivey A., Walker A.R.,
RA   Woodward J., Dobbelaere D.A.E., Langsley G., Rajandream M.A., McKeever D.,
RA   Shiels B., Tait A., Barrell B.G., Hall N.;
RT   "Genome of the host-cell transforming parasite Theileria annulata compared
RT   with T. parva.";
RL   Science 309:131-133(2005).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC       subfamily. {ECO:0000256|ARBA:ARBA00038423}.
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DR   EMBL; CR940353; CAI76266.1; -; Genomic_DNA.
DR   RefSeq; XP_952890.1; XM_947797.1.
DR   AlphaFoldDB; Q4UA87; -.
DR   STRING; 5874.Q4UA87; -.
DR   GeneID; 3862728; -.
DR   KEGG; tan:TA07280; -.
DR   VEuPathDB; PiroplasmaDB:TA07280; -.
DR   eggNOG; KOG2023; Eukaryota.
DR   InParanoid; Q4UA87; -.
DR   OMA; XYMLQRT; -.
DR   OrthoDB; 276400at2759; -.
DR   Proteomes; UP000001950; Chromosome 4.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001950}.
FT   DOMAIN          55..94
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03810"
SQ   SEQUENCE   959 AA;  107537 MW;  6D2199E622DD6CF5 CRC64;
     MPLDRALYSQ LLEILTLSEK GDTETQKYVH ESLASFQNNR ADVPLYYLEA SLSGPTFHTK
     QMALLLLKNS VLQNWNKTDP AIQSVIKNEI INIVNLREVK LRNAVASCYV SIFNVQGYDQ
     WPTGLYNLLS IISNSASTVG SEEVDEVVET AVVTLVMILE DTISNGAMTP NYLNYLKSDF
     IVKLFQITSK SPALTEITSR ILLTLLDSNV ILEYLVSDLF GQFWNLLGVM ATLDNYNVKK
     CVLKAMHNLW DLVPMSILQS SDALFPFISK LCSDDAYTIQ IDALDFYTHI LQSQLYTSSN
     NQIRCLLLGK MANEFGTLLK TLVDNTKYSS WDYMSMDRTH LEDDNANIPD DMQDVPIKTR
     EDEETNTWGN TWTVRKGSAL LLDTISQLYA QSNPEVIKIL LSYIQEKLDS TDWELKESGV
     LTLGAISKGS LYTLYPYLPK VIDYLIVVAT DPKPLLRIIS CWCLSRFVEW MFLPNNTNTY
     LSKTLSVILR GMLDRNKRVQ ESACSSFTSF EECGTTLLLP YAGQILHVIL SCIELYQSRN
     FMILYDVIGT LYQSLGESIT QQAEHNQLID VLLNRLEIVG LGDVQYIGLI ECLSSIISVL
     GSKLPQFFVQ KITKHCVSSL CELVGDITEL EYFYQSVQVL TDTISILLTS TQGSVNCNEA
     CNVINGLRIS NGIDLVIVIN ELCSSKISVI LQSCIALMGD LSNSSIQLNQ DSLKVLVDNV
     QNYINNIQSC PNPNEQSSIN SSSTNVQSRL NSINSREESD EYYGVVNNCV WVFGVLCDNQ
     LGIYNSSNID LVFLLVVKVI NLCSNNFCIL QNCCVTLGKF SNHFPNVAIK YLNSFLNPLC
     KHLIHSKNDK EKFNTTLSIS NLILLHLQSN NTQSVNSLGN VIKIGKEELE TCNVLLLFKL
     YISCTKGTLD NFGDSFGTNS DLIQVCVNLI KSLLYQHPKL VQLIDPDTKN QLNSLTSLT
//