ID Q4UAX3_THEAN Unreviewed; 926 AA.
AC Q4UAX3;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Transcription factor, putative {ECO:0000313|EMBL:CAI76028.1};
GN ORFNames=TA18410 {ECO:0000313|EMBL:CAI76028.1};
OS Theileria annulata.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=5874 {ECO:0000313|EMBL:CAI76028.1, ECO:0000313|Proteomes:UP000001950};
RN [1] {ECO:0000313|EMBL:CAI76028.1, ECO:0000313|Proteomes:UP000001950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ankara {ECO:0000313|Proteomes:UP000001950};
RX PubMed=15994557; DOI=10.1126/science.1110418;
RA Pain A., Renauld H., Berriman M., Murphy L., Yeats C.A., Weir W.,
RA Kerhornou A., Aslett M., Bishop R., Bouchier C., Cochet M., Coulson R.M.R.,
RA Cronin A., de Villiers E.P., Fraser A., Fosker N., Gardner M., Goble A.,
RA Griffiths-Jones S., Harris D.E., Katzer F., Larke N., Lord A., Maser P.,
RA McKellar S., Mooney P., Morton F., Nene V., O'Neil S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rawlings N.D., Rutter S., Saunders D.,
RA Seeger K., Shah T., Squares R., Squares S., Tivey A., Walker A.R.,
RA Woodward J., Dobbelaere D.A.E., Langsley G., Rajandream M.A., McKeever D.,
RA Shiels B., Tait A., Barrell B.G., Hall N.;
RT "Genome of the host-cell transforming parasite Theileria annulata compared
RT with T. parva.";
RL Science 309:131-133(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SPT5 family.
CC {ECO:0000256|ARBA:ARBA00006956}.
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DR EMBL; CR940352; CAI76028.1; -; Genomic_DNA.
DR RefSeq; XP_955504.1; XM_950411.1.
DR AlphaFoldDB; Q4UAX3; -.
DR STRING; 5874.Q4UAX3; -.
DR GeneID; 3864756; -.
DR KEGG; tan:TA18410; -.
DR VEuPathDB; PiroplasmaDB:TA18410; -.
DR eggNOG; KOG1999; Eukaryota.
DR InParanoid; Q4UAX3; -.
DR OMA; FLAWDVE; -.
DR OrthoDB; 211200at2759; -.
DR Proteomes; UP000001950; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0006354; P:DNA-templated transcription elongation; IEA:InterPro.
DR GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd06081; KOW_Spt5_1; 1.
DR CDD; cd06084; KOW_Spt5_4; 1.
DR CDD; cd09888; NGN_Euk; 1.
DR Gene3D; 2.30.30.30; -; 3.
DR Gene3D; 3.30.70.940; NusG, N-terminal domain; 1.
DR InterPro; IPR005824; KOW.
DR InterPro; IPR041973; KOW_Spt5_1.
DR InterPro; IPR041977; KOW_Spt5_4.
DR InterPro; IPR005100; NGN-domain.
DR InterPro; IPR036735; NGN_dom_sf.
DR InterPro; IPR039385; NGN_Euk.
DR InterPro; IPR014722; Rib_uL2_dom2.
DR InterPro; IPR039659; SPT5.
DR InterPro; IPR017071; TF_Spt5_eukaryote.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR PANTHER; PTHR11125; SUPPRESSOR OF TY 5; 1.
DR PANTHER; PTHR11125:SF7; TRANSCRIPTION ELONGATION FACTOR SPT5; 1.
DR Pfam; PF00467; KOW; 1.
DR Pfam; PF03439; Spt5-NGN; 1.
DR PIRSF; PIRSF036945; Spt5; 2.
DR SMART; SM00739; KOW; 5.
DR SUPFAM; SSF50104; Translation proteins SH3-like domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001950}.
FT DOMAIN 265..292
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT DOMAIN 433..460
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT DOMAIN 484..511
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT DOMAIN 614..641
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT DOMAIN 688..715
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT REGION 1..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..37
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 926 AA; 101809 MW; 21E9CADE60F20A70 CRC64;
MNEESPSNSD LFGDDVPEDT STLLDDLTTE LDELTEEAPV EETKKKRSRK LKKRDSSKKR
KIDVSAFLDT EAQVGDDEDE NYEYDFLLPD ESTEAERLEH RSRLKRLQDD KRDDRRIGGT
QYLETAIDKL AKRYQDQTFE EGEDEIQESQ PIEYDGIEET SALIPDLGDP KLWIVRTNRQ
TPDRNLAISI MNKSLRYQSM GKNLGIYSCF VPDGVTGYLY IEADNKTTVI EALSEFRQIS
LNTLKLVPIN EMSNVFTTGF DNVYIPRVGE FVRVKFGRYA GDLGQVYESD ENTSTVTLKL
IPRIDPSILS NNDNFNDGFD GIDSINSIGT VGTAAPVNGV KKNIKYNKML FDRDAVELNG
GLIEHGIIPG TFRYQGMTFL DSGHILQKFS SKRLVTQDAV NPTLAELREF STDSSLTEVL
SHVTRSAGSK SALYKLGDRV KVVKGELMSV TGKIIGVEAE EVEVQPDDKE LPNFRINLNS
VIKDLVEGDN VRAIGGSNEG KTGLVVMVNA KNRSALVFSP QTGEEFKSTL EHLALIPREG
LGDEGSKVGG INGFVVTDLV QTTSGEVGVI ISVERSGSVT ILTDGNNRLK VSPGQITCKR
TSVGSSSRDF NNQPIEPRQR VMVVRGNYRN KTGQVLHLWR NTLFLSVEND VIVVSSTDCL
RAGNATSTAT KPVTTNAPIG NVKLVRKNPL IGKTVKILQG RYKGLLGDII HVEPTQFTIL
LKVKPKTVRY PKSECVILDN WHHNIRYANT YSNNSRINTT STVLGSTGIN SNMDTYSTVT
TTTDINALAN TNTTVPTNTT TPGTTVSGIV ENKMSPWSVE GVVVKVIGPG GYYGKMGVVG
EVFENMVDTS LQVLHVMVEE DYIAIAAESV EPVPPSKPGE QALVFSMGKD KFGTVVNVSG
DKVTVKLTTG DVVTVDKEGV ALMSQQ
//
