ID   Q4UG59_THEAN            Unreviewed;       703 AA.
AC   Q4UG59;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   27-MAR-2024, entry version 80.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN   ORFNames=TA20070 {ECO:0000313|EMBL:CAI73930.1};
OS   Theileria annulata.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC   Theileriidae; Theileria.
OX   NCBI_TaxID=5874 {ECO:0000313|EMBL:CAI73930.1, ECO:0000313|Proteomes:UP000001950};
RN   [1] {ECO:0000313|EMBL:CAI73930.1, ECO:0000313|Proteomes:UP000001950}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ankara {ECO:0000313|Proteomes:UP000001950};
RX   PubMed=15994557; DOI=10.1126/science.1110418;
RA   Pain A., Renauld H., Berriman M., Murphy L., Yeats C.A., Weir W.,
RA   Kerhornou A., Aslett M., Bishop R., Bouchier C., Cochet M., Coulson R.M.R.,
RA   Cronin A., de Villiers E.P., Fraser A., Fosker N., Gardner M., Goble A.,
RA   Griffiths-Jones S., Harris D.E., Katzer F., Larke N., Lord A., Maser P.,
RA   McKellar S., Mooney P., Morton F., Nene V., O'Neil S., Price C.,
RA   Quail M.A., Rabbinowitsch E., Rawlings N.D., Rutter S., Saunders D.,
RA   Seeger K., Shah T., Squares R., Squares S., Tivey A., Walker A.R.,
RA   Woodward J., Dobbelaere D.A.E., Langsley G., Rajandream M.A., McKeever D.,
RA   Shiels B., Tait A., Barrell B.G., Hall N.;
RT   "Genome of the host-cell transforming parasite Theileria annulata compared
RT   with T. parva.";
RL   Science 309:131-133(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR   EMBL; CR940347; CAI73930.1; -; Genomic_DNA.
DR   RefSeq; XP_954607.1; XM_949514.1.
DR   AlphaFoldDB; Q4UG59; -.
DR   STRING; 5874.Q4UG59; -.
DR   GeneID; 3864459; -.
DR   KEGG; tan:TA20070; -.
DR   VEuPathDB; PiroplasmaDB:TA20070; -.
DR   eggNOG; KOG0922; Eukaryota.
DR   InParanoid; Q4UG59; -.
DR   OMA; WVVFNES; -.
DR   OrthoDB; 228104at2759; -.
DR   Proteomes; UP000001950; Chromosome 1 part 1.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF136; ATP-DEPENDENT RNA HELICASE DHX35-RELATED; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00847; HA2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:CAI73930.1};
KW   Helicase {ECO:0000313|EMBL:CAI73930.1};
KW   Hydrolase {ECO:0000313|EMBL:CAI73930.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:CAI73930.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001950}.
FT   DOMAIN          433..533
FT                   /note="Helicase-associated"
FT                   /evidence="ECO:0000259|SMART:SM00847"
SQ   SEQUENCE   703 AA;  82107 MW;  6E850C7D00F995EB CRC64;
     MERVIEKYKN QIVHSVEEYN VLVLSGYPDS YMYSFVPFYL FNRGFTDQVK QTPNPPKICT
     VFNNKQDVLY FSDLCSALVS DQSKVKYLMM VFYCLTKILV TTILDDNSNY NKKSEIVYTT
     DEYIIRKLLV DPLLSEFSVF VLCNLQERPI NMDVLLALFK RLLNVRKRLR LVLLYQSTNV
     NYILEYFKRE TSNESNEPDN VPTPDFCLGD FPLKDVQYIY LENEFSFYKV NYLSRPTSNY
     LETLISTVYD ICKNESRDNI LIFVPTREHA HLLKAELEEI ANQFSSDKGI INVMCLRANI
     YMEEKENVLR NIFICTDVND YNFGMGEITY LVDSCLTRRL SSEYLNTGMS ENITPSTREE
     MMIKSSLIHN VRRGLCYRLM TQDDYNSIVQ EFIVPEIMTK DLTLMVLLLK SLGISKLSDF
     DFLTKPPAES LKHSLFTLYM LGAIDASGEL VYPIGNLMAE LRVTPYLSSF LYRSVESGCS
     EEALIIYSML QVKEILWKKS CKIYRNESSY HTDRLESAKL AFAALEGDLV SYFNMFQLSQ
     YYKDEDDRWL SVHMVNERAI QMAEKIKTKT TKLLAKYDLE TNSCDGNVEL LIKTIFSSFF
     LNVACKEYLV QNFQNSNQII SHLKDNKPLH VSDPKIEDQQ PYVLVKSYQK FNYKPLYIHP
     SSFIVNEQPD WVVFNESNTI DGKLYMHDVT TIRPEYLNWL LYT
//