ID Q4W9R3_ASPFU Unreviewed; 600 AA.
AC Q4W9R3;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=AFUA_4G04010 {ECO:0000313|EMBL:EAL84550.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL84550.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL84550.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL84550.1}.
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DR EMBL; AAHF01000016; EAL84550.1; -; Genomic_DNA.
DR RefSeq; XP_746588.1; XM_741495.1.
DR AlphaFoldDB; Q4W9R3; -.
DR SMR; Q4W9R3; -.
DR ESTHER; aspfu-q4w9r3; Fungal_carboxylesterase_lipase.
DR EnsemblFungi; EAL84550; EAL84550; AFUA_4G04010.
DR GeneID; 3503910; -.
DR KEGG; afm:AFUA_4G04010; -.
DR VEuPathDB; FungiDB:Afu4g04010; -.
DR eggNOG; KOG4389; Eukaryota.
DR HOGENOM; CLU_006586_10_6_1; -.
DR InParanoid; Q4W9R3; -.
DR OMA; EYGYDCP; -.
DR OrthoDB; 3085104at2759; -.
DR Proteomes; UP000002530; Chromosome 4.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF421; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 22..600
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5005143404"
FT DOMAIN 111..566
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 600 AA; 66321 MW; D625F56897F96531 CRC64;
MARRISSLAW LSLLLGALSR ALPSSQTQGA IADYPTATLR TSYQSGSKTV FVGRSLPEFD
QELFLGIKYA DQPIRFTPSS LKTSYAANDS NSGPYDASGT GLALSKGTVL YNATQYGHEC
PGYGSDETKL VDMGLITLHE DCLNLNIIRP TRKSDNEELL PVMIWIFGGG WQQGATADPR
YNMSYILRQG ALNGKPVLGV SINYRVAAFG FLDSEEVRAT GNNNLGLRDQ RVAMRWVKEN
IKAFGGDPDK VTIWGESAGA YSVGAHLVAN GGDNEGLFRA AIMESGNAVG PPWNGTDWHQ
PMYDRIVNKA GCSTSSDTLQ CLREVPYQSL YDIAYEGLEW FAAIDGSFIK EYPQISYTEG
RLAKVPILLG SNTDEGTSFG TTGTNTDEEC INQLICGFFC RPRQRLVLTM TASKRWVLTR
EEATRLLTYY PNDPALGCPY GWGNVTWPKL GLMYKRYESM AGDLTMVAPR RLLAQTMAKY
TKQVYSYRWD VPALNTSSTI GVGHFAEIPF VFANPVQNIT PLGTDPSRLE LGNMAARMWT
SFVTDLNPNG HGVPRIPQWP KYTPGKKASN FVFRLPANGS YVERDDYRLD GMDYINNIAR
//
