ID Q4WEN9_ASPFU Unreviewed; 445 AA.
AC Q4WEN9;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 24-JAN-2024, entry version 116.
DE SubName: Full=Transcription initiation factor TFIID complex 60 kDa subunit {ECO:0000313|EMBL:EAL85938.1};
GN ORFNames=AFUA_5G03680 {ECO:0000313|EMBL:EAL85938.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL85938.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL85938.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF6 family.
CC {ECO:0000256|ARBA:ARBA00007688}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL85938.1}.
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DR EMBL; AAHF01000011; EAL85938.1; -; Genomic_DNA.
DR RefSeq; XP_747976.1; XM_742883.1.
DR AlphaFoldDB; Q4WEN9; -.
DR STRING; 330879.Q4WEN9; -.
DR EnsemblFungi; EAL85938; EAL85938; AFUA_5G03680.
DR GeneID; 3505478; -.
DR KEGG; afm:AFUA_5G03680; -.
DR VEuPathDB; FungiDB:Afu5g03680; -.
DR eggNOG; KOG2549; Eukaryota.
DR HOGENOM; CLU_021711_3_0_1; -.
DR InParanoid; Q4WEN9; -.
DR OMA; YFVQFIA; -.
DR OrthoDB; 1529at2759; -.
DR Proteomes; UP000002530; Chromosome 5.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR GO; GO:0000124; C:SAGA complex; IEA:EnsemblFungi.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:EnsemblFungi.
DR GO; GO:0005669; C:transcription factor TFIID complex; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IEA:EnsemblFungi.
DR GO; GO:0042802; F:identical protein binding; IEA:EnsemblFungi.
DR GO; GO:0060090; F:molecular adaptor activity; IEA:EnsemblFungi.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR GO; GO:0061629; F:RNA polymerase II-specific DNA-binding transcription factor binding; IEA:EnsemblFungi.
DR GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR GO; GO:0006325; P:chromatin organization; IEA:EnsemblFungi.
DR GO; GO:2000144; P:positive regulation of DNA-templated transcription initiation; IEA:EnsemblFungi.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:EnsemblFungi.
DR GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IBA:GO_Central.
DR CDD; cd08050; TAF6C; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.25.40.770; TAF6, C-terminal HEAT repeat domain; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037796; TAF6.
DR InterPro; IPR011442; TAF6_C.
DR InterPro; IPR046344; TAF6_C_sf.
DR InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR PANTHER; PTHR10221; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR PANTHER; PTHR10221:SF9; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR Pfam; PF02969; TAF; 1.
DR Pfam; PF07571; TAF6_C; 1.
DR SMART; SM00803; TAF; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..66
FT /note="TATA box binding protein associated factor (TAF)
FT histone-like fold"
FT /evidence="ECO:0000259|SMART:SM00803"
SQ SEQUENCE 445 AA; 48735 MW; 447C5B1034208D15 CRC64;
MSVWNPDNIR DVAESVGIVN LSNDVTENLA RDVEYRIAQV LEEALKFMRH SRRTLLTTQD
VAQALRVLDV EPLYGYETTR PLRFGEASLG PGQPLFYVED EEVDFEKLIN APLPKVPREI
SFTAHWLAVE GVQPSIPQNP TAADSRNLEL TAKGPNANST LAAMSGTGDV AVKPLVKHVL
SKELQLYFEK VCNAFLDESS EEYRTSGYAS LREDPGLHQL VPYFVQFISE KVTHGLKDIF
VLTQVMHMAE ALVQNKSLYV DPYIASLVPP ILTCLIGRQL GGNADLSEQF ALRDLAGSLL
GLISKKYSHS SHTLTPRLAR SCLKTFLDPS KPFGAHYGAI IGLHAVGGTE AVRVLILPNL
STYATLLADG MAEDNPRRPE AEKVLGALLA VLSTLREGRK TLANGHGAIV TDELRERLNA
KVGDIIASRI ADAGEVQMVY AILEA
//
