ID Q4WHH1_ASPFU Unreviewed; 717 AA.
AC Q4WHH1;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Pre-rRNA processing protein Esf1, putative {ECO:0000313|EMBL:EAL87634.1};
GN ORFNames=AFUA_2G05420 {ECO:0000313|EMBL:EAL87634.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL87634.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL87634.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the ESF1 family.
CC {ECO:0000256|ARBA:ARBA00009087}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL87634.1}.
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DR EMBL; AAHF01000008; EAL87634.1; -; Genomic_DNA.
DR RefSeq; XP_749672.1; XM_744579.1.
DR AlphaFoldDB; Q4WHH1; -.
DR STRING; 330879.Q4WHH1; -.
DR EnsemblFungi; EAL87634; EAL87634; AFUA_2G05420.
DR GeneID; 3507129; -.
DR KEGG; afm:AFUA_2G05420; -.
DR eggNOG; KOG2318; Eukaryota.
DR HOGENOM; CLU_010564_0_1_1; -.
DR InParanoid; Q4WHH1; -.
DR OMA; YEMEMSW; -.
DR OrthoDB; 131620at2759; -.
DR PHI-base; PHI:2547; -.
DR Proteomes; UP000002530; Chromosome 2.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR InterPro; IPR039754; Esf1.
DR InterPro; IPR012580; NUC153.
DR PANTHER; PTHR12202:SF0; ESF1 HOMOLOG; 1.
DR PANTHER; PTHR12202; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT DOMAIN 630..658
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 74..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 211..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 432..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 640..717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..97
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..116
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..150
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..234
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..249
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..487
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..572
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..685
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 717 AA; 82271 MW; CD3B08B9BA433505 CRC64;
MLTLDCLLLA DPRFANIQTD PRYRLPSKRQ THVKLDKRFA HMLRDKDFSR NAAVDRYGRK
LARDDTKKQL ERFYQLEGDE EGDKDEDEDE EGDGIVADDD DEVRKELKRI DKAYDPARDG
GFSSSSSEEE SSSDEESEEE DDEEEQSIEE LDFPDKQQVD VPTGEVTNRI AVVNLDWDNI
RAEDLMAVFS SFVPTGGRVL KVSVYPSEFG KERMEREETE GPPREIFATN KRQEDDDEEN
EEDLDSEEEE EKIKQSILKE DQGEEFNSTQ LRKYQLERLR YFYAILTFSS KDVAKHVYDS
VDGAEYLSSA NFFDLRFVPE DTDFSDDKPR DECERIPDGY QPNEFVTDAL QHSKVKLTWD
AEDKSRKEAQ ARAFRGSRKD IDENDLKAYL ASDSSDDEGE EEAVEVVDTT KGDGSSTKIS
KKEEERQRLR ALLGLSTEPL KSSKSSGPVG EMEVTFTSGL AGEPKRDTIF ENEPEREETT
IEKYIRKERE RKKRRKEKLK ALKRGETQGE AKADANGDDV SSAGEGQAAH EDLGFNDPFF
DDPDGKATAA ARRKEEKRKK RAEREAEEAA NAAKRAELEL LMLDDKKSEI KHFDMNEIEK
AQKQARKKNK KKAKDQAQTV NDDFQMDVSD PRFARLFESH EYAIDPTNPK FKPTPGMKAL
LDEGRKRRRD RDDRGDEEVS TSRDRKKKKQ KQSAAGNAGS DDLKKLVDKV KRNTQQT
//
