ID Q4WMC6_ASPFU Unreviewed; 1240 AA.
AC Q4WMC6;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Cullin binding protein CanA, putative {ECO:0000313|EMBL:EAL88888.1};
GN ORFNames=AFUA_6G10380 {ECO:0000313|EMBL:EAL88888.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL88888.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL88888.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SIMILARITY: Belongs to the CAND family.
CC {ECO:0000256|ARBA:ARBA00007657}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL88888.1}.
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DR EMBL; AAHF01000006; EAL88888.1; -; Genomic_DNA.
DR RefSeq; XP_750926.1; XM_745833.1.
DR AlphaFoldDB; Q4WMC6; -.
DR STRING; 330879.Q4WMC6; -.
DR EnsemblFungi; EAL88888; EAL88888; AFUA_6G10380.
DR GeneID; 3508231; -.
DR KEGG; afm:AFUA_6G10380; -.
DR VEuPathDB; FungiDB:Afu6g10380; -.
DR eggNOG; KOG1824; Eukaryota.
DR HOGENOM; CLU_007157_0_0_1; -.
DR InParanoid; Q4WMC6; -.
DR OMA; AYIPHFQ; -.
DR OrthoDB; 68829at2759; -.
DR Proteomes; UP000002530; Chromosome 6.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR GO; GO:0010265; P:SCF complex assembly; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039852; CAND1/CAND2.
DR InterPro; IPR007175; Rpr2/Snm1/Rpp21.
DR InterPro; IPR013932; TATA-bd_TIP120.
DR PANTHER; PTHR12696:SF0; CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1; 1.
DR PANTHER; PTHR12696; TIP120; 1.
DR Pfam; PF04032; Rpr2; 1.
DR Pfam; PF08623; TIP120; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1059..1225
FT /note="TATA-binding protein interacting (TIP20)"
FT /evidence="ECO:0000259|Pfam:PF08623"
FT REGION 107..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..407
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1240 AA; 135210 MW; E4312CFFBCE7C65B CRC64;
MPISDHTPRL NFLKDSASVL DSLSPSTASH LLMVHNRVLH DEFKPLTQRQ LDFACGACGS
IRKPERTKTI EIRKKKAKSS SSFAPKKSSA LGATIYKCLR CHRRTVKPAA RPNIKSKPDT
TAAPVPTTQS TTSTTTAKYV SPTAQSGEAD RSSKTADNAS SKKRAKARKQ GGLQALLASK
QQSQSKSSAS LDLFDFLQQQ MSSDSMSDYS HDEEHDPQAD ELRETALVTL ETLISSCSQQ
MQPYLANAVK SSLRFLKYDP NVADVEDDEE MGGTQDDGSE DDATEEPDLE DDEFGDFEDE
GGYSDIDDMS WKVRRCAAKL LYTVISTYGR TRALDDTSLY QQIAPALIAR FKKEREESVK
LEVVSTMTAL VRKTSEGAMI ITSNGFLESV GGSKNSRKRR RQDSDASMID FEPSIGTSSA
ISTPVIAPSS PTTGPQAELS RSVPVIVQSL VKMWKSASVP LKQAIIVLLK SLALVRYGGL
ADHLQQIEDP IADVLKSSST GSVTSTVGPA VSAGALQTET LSLVAAIAET HTSDALLPFL
IALIPGVIGA VNDRNYKVSS EALGAVEQII KALTPPRVTA SSPDLVSQLE KLYDEILSRI
TDTSADLEVR QRAIHVFGVL LARTSGEKGA DFLSPDRRLK GLSVLVDRLR NETTRLASVR
AVDDVAVLCT KETDVTASWV SEVTVELGAQ LRKSDRVLRG ASLETLRSLA MNPSTRAHYD
GKTMKELEDC LLPLISADDF HFLAPSLIIL AKLIPGNAQL LVNEGLVSAL CSIVLAPLVG
TVLKALLLLV KVIGEEGAGA ELMQKLLRDV GINGDPSVVG RAIGTLLVHG GSKLGVKMED
FLTELQTAQD AQRKCLALAI IGEIGLRMGP ACSLTPDLFI THFESKSDKV RLAAATALGN
AAAGNVKTYM PIILDGFTKS NPRSYLLLHS VKELLQHPEI VRPDVAPIAV KLWQALLLVS
EEEDNRAVGA ECIGRLALID PVAYIPHFQD YLSSSDPNIR GVVISAFRYT LTDSRGSYND
VLRPLIVPLL VNMLSDRDLG NHRLALTTLN SAIHNKMNII LPHLSELLPA VFGDTQVKPE
LIREVQMGPF KHKVDDGLEL RKSAYETLYA SLDTAFSVAH VSEFFDRILA GLEDEQDIRT
ICNLMTSKLI PIAPEETQRY LDQLSERYSA VLSFKPKDNA VKQELEKAQE ASMGILKVTR
ELSKAFPNAE VSGDHHKWKA YMEWVRKTFA TQLKSLETEF
//
