ID Q4WS26_ASPFU Unreviewed; 761 AA.
AC Q4WS26;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=Protein CASP {ECO:0000256|ARBA:ARBA00018691};
GN ORFNames=AFUA_1G14240 {ECO:0000313|EMBL:EAL90756.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL90756.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL90756.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-
CC pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the CASP family.
CC {ECO:0000256|ARBA:ARBA00006415}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL90756.1}.
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DR EMBL; AAHF01000004; EAL90756.1; -; Genomic_DNA.
DR RefSeq; XP_752794.1; XM_747701.1.
DR AlphaFoldDB; Q4WS26; -.
DR STRING; 330879.Q4WS26; -.
DR EnsemblFungi; EAL90756; EAL90756; AFUA_1G14240.
DR GeneID; 3509805; -.
DR KEGG; afm:AFUA_1G14240; -.
DR VEuPathDB; FungiDB:Afu1g14240; -.
DR eggNOG; KOG0963; Eukaryota.
DR HOGENOM; CLU_016758_0_0_1; -.
DR InParanoid; Q4WS26; -.
DR OMA; FAGYCFA; -.
DR OrthoDB; 1643779at2759; -.
DR Proteomes; UP000002530; Chromosome 1.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR InterPro; IPR012955; CASP_C.
DR PANTHER; PTHR14043; CCAAT DISPLACEMENT PROTEIN-RELATED; 1.
DR PANTHER; PTHR14043:SF2; HOMEOBOX PROTEIN CUT; 1.
DR Pfam; PF08172; CASP_C; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 695..713
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 458..716
FT /note="CASP C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08172"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 610..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 739..761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 267..301
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 434..489
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 554..602
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 9..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 761 AA; 83827 MW; 807344D571A0EBE3 CRC64;
MDTFAITEGI VPENNNQDGH DAEPASSAQQ LPEEANKFQR AIAAWRSIDL TTTVAKLDAT
ASDIVAQQRD ALIQRKELAQ KTKDFRKLDD ASKLAEYKGL LKSYQSFIDL LTNHGKSSSS
AFLQLYSSLS EAPDPYPLLE ASVDSLVLSE QTVPKLTSER DQLQRSVSRL TTQLEDTEKR
LQEERAARRN LEDSQETKIK EIESSWSAVL AEKSNNWAAK EKSLEEKVEN QDRLLKEIKA
SYEVSQRLGQ ENDGSDASQH GATAAELELV SADLEKTTLR LAEVEARNEQ LRLELAQAVS
HSQATQPTSV EDDPAYLRLQ SENSSLLRKL DAARFDRESE RHSWESKLSQ LERQSSKVAA
ERDELRSRLE KTADYEDIRR ELEMIKSIEF SAGDGDDDEV GDSTGNANGT NSALLKPKDG
SSGNSLEGLL LARNKKLTDE LTVLRVSHRD LQDQLELLRE DLSNTKEELE KSKQLSTTLE
NDLLRVQQEA ANAFPSSAMS VAGTYSSRYP HSTRRGAASP TSSIISGFDQ AATSSNAMDA
IRAGEPVGGG SGLLPMIQAQ RDRFKKKNAE LEEELSKMYS TVKSLRQEVA SLQKDNLSLY
EKTRYVSTYS RGGASSSASA YANKPSNSSV HVSADTPSGL SLDRYQSAYE ARLSPFAAFR
GRESVRAYKR MSLPERIVFS ITRIILANRT SRNLFAGYCF ALHVLLFLAL YMMSTMEIEK
HSSASLGAAA AAAMAGGGGS GSSSGQLHGD DWQQEGFNHA A
//
