ID Q4WU37_ASPFU Unreviewed; 831 AA.
AC Q4WU37;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=DUF803 domain membrane protein {ECO:0000313|EMBL:EAL91889.1};
GN ORFNames=AFUA_5G07070 {ECO:0000313|EMBL:EAL91889.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL91889.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL91889.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL91889.1}.
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DR EMBL; AAHF01000003; EAL91889.1; -; Genomic_DNA.
DR RefSeq; XP_753927.1; XM_748834.1.
DR AlphaFoldDB; Q4WU37; -.
DR EnsemblFungi; EAL91889; EAL91889; AFUA_5G07070.
DR GeneID; 3511042; -.
DR KEGG; afm:AFUA_5G07070; -.
DR VEuPathDB; FungiDB:Afu5g07070; -.
DR eggNOG; KOG2922; Eukaryota.
DR HOGENOM; CLU_012349_2_1_1; -.
DR InParanoid; Q4WU37; -.
DR OMA; VMQIRYI; -.
DR OrthoDB; 2906343at2759; -.
DR Proteomes; UP000002530; Chromosome 5.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015693; P:magnesium ion transport; IBA:GO_Central.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF93; DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070); 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 60..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 134..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 479..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 572..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 670..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 732..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 786..831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..648
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..764
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..831
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 831 AA; 90582 MW; 58DCEE723C368054 CRC64;
MASFQEDPLA AGLLTGLVTS FAPTPTTAAS VSSSFRHLPS STSGSDSSIG GHNGGHLHEW
SSLIGIVTAL VGNVLISLAL NIQRYAHIRI EREWEQSKLQ REIQWKRANS GRNAAGAYGT
TVAEEDDREF RRGGRLFPRY RDESPDSGPE LPEDFLRRSD EFSDGESGPR GRLRESFLSD
QTIRAGDKDS RHGRRKSYLR SPYWWAGLVL MCLGEIGNFM AYGFAPASIV SPLGVVALIS
NCVIAPIMLK EKFRQRDAWG VLIAIAGAVV VVLSASSSEE KIGPHDIWVM ITRWEFELYL
GLTACLIITL MWVSHKYGSR TILIDVGLVA LFGGYTALST KGVSSLLSFT LWHVITFPVT
YLLVFVLVFS ALMQIRYINR ALQRFDSTQV IPTQFVLFTL SVIVGSAVLY RDFENYTVER
ASKFVSGCLM TFLGVYFITS GRLRADDESS FSIDDEEEAI GLLGGEQYQD NFDIARPAHQ
PRTAKRGQRQ SIPDENDLQS PLGSFLGSGI EDVDEDQLTP KGALSAAPSS PVGSITAESP
TQPSPGHPSL HSHSHSLLTN PWADHLEQHV QASNSEPQLH RPATPPEQSE TGNADSAVLL
QFPPAPGIEN RGYRPSSPSK PDHVEPADRE STVPQTPPAR NLRNSISKHF SPGPLLPTLS
AGFSAVVAES LRRGETSPVK DRKSHKRSAR RKQLSTTVFD GYTRNRDRGP SDEVDAGVDQ
HLPLQLATAR LRSTGDLPTP PGPVGNPTPL VDSEDQSISQ SGNGVTTLTR IRSLSDSWSG
GLAWLGGALR KPNSSNKALD STTTVEADEN HSRTETHDRG GGRESGTDTR T
//
