ID Q4WVU8_ASPFU Unreviewed; 786 AA.
AC Q4WVU8;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 2.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=BRCT domain protein {ECO:0000313|EMBL:EAL91278.2};
GN ORFNames=AFUA_5G13380 {ECO:0000313|EMBL:EAL91278.2};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL91278.2, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL91278.2, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL91278.2}.
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DR EMBL; AAHF01000003; EAL91278.2; -; Genomic_DNA.
DR RefSeq; XP_753316.2; XM_748223.2.
DR AlphaFoldDB; Q4WVU8; -.
DR STRING; 330879.Q4WVU8; -.
DR EnsemblFungi; EAL91278; EAL91278; AFUA_5G13380.
DR GeneID; 3511179; -.
DR KEGG; afm:AFUA_5G13380; -.
DR eggNOG; KOG1929; Eukaryota.
DR HOGENOM; CLU_009893_1_1_1; -.
DR InParanoid; Q4WVU8; -.
DR OMA; FATQWNI; -.
DR OrthoDB; 20296at2759; -.
DR Proteomes; UP000002530; Chromosome 5.
DR GO; GO:0005694; C:chromosome; IEA:UniProt.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0006270; P:DNA replication initiation; IBA:GO_Central.
DR GO; GO:0033314; P:mitotic DNA replication checkpoint signaling; IBA:GO_Central.
DR GO; GO:0007095; P:mitotic G2 DNA damage checkpoint signaling; IBA:GO_Central.
DR CDD; cd17740; BRCT_Rad4_rpt1; 1.
DR CDD; cd18433; BRCT_Rad4_rpt3; 1.
DR CDD; cd17723; BRCT_Rad4_rpt4; 1.
DR CDD; cd17731; BRCT_TopBP1_rpt2_like; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 4.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR PANTHER; PTHR13561; DNA REPLICATION REGULATOR DPB11-RELATED; 1.
DR PANTHER; PTHR13561:SF20; DNA TOPOISOMERASE 2-BINDING PROTEIN 1; 1.
DR Pfam; PF12738; PTCB-BRCT; 3.
DR SMART; SM00292; BRCT; 4.
DR SUPFAM; SSF52113; BRCT domain; 4.
DR PROSITE; PS50172; BRCT; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT DOMAIN 22..95
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 117..206
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 326..427
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 439..525
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 222..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 653..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..573
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..633
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..675
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..705
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 756..770
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 786 AA; 87314 MW; 911AA9BAE10A91BA CRC64;
MKHGTELDFH VRDCGTANNA SDKERPLSGV VLCFTSILPE QRTELATIAS QMGAAHKFDL
TSDVTHLLVG EINTAKYKFV ARERSDVVVL KPEWVEAVRQ SWMQGEDTDI RALEQQYRLP
TFMGLAICIT GFEDMAYRNY IQDTAIAHGA DFRKDLTKSV THLIARNTEG QKYKFATQWN
IKVVTMKWFT DSIERGMVLE ETLYHPLLPQ EQQGVGAWNR TAPPAKEKAA DAENSSNPRP
RKLRRIASTK LVDQNEGIWN AIVGAGFENN ELRLSTNSQL KNEDVTSSKI TRKASVVQEA
KSFASETTFA EAQGSRQDTS EVRQASNNGF LDGCYFFIYG FSPKQTSVLR HHLSYNGAQL
VSSLSELSRP AIPKRGHGLY KIVSYKTPRS EIPSTDDLAF DCDVVTDMWL ERCLEAKTLV
PPESHIACTP LPVFPIPGFH GMKICSTGFS RIDLLHLSKL VDLIGATYDE YLTPKASVLV
CNNSGSINNE KLRHTSEWKI PAVRVDWLWS SIKSGQRKAF EPYIIQRLSQ HEKSLEVRAG
SRTEQKDVFE SSDKPNRSAK SDSGTRESKK HGINGSTKST PVEKPSKPSS EDESVKAPPP
YKRPSQSASV SPTKETRPPN TASPSNKRKA PDHVTTSAQA AIELAVSGFL KQARTANSRS
KSDTTDQESD SLRRRRRKPL LGRAPSHSSA QGVFSRASSI DTLNEDGCGS AVESIGAEGF
NSFLTGGRFE PSESQRRIED QENEEPAMTQ LNYEDPDAVK MREELFSHAG KLSNKTKSSD
TGRDRG
//
