ID Q50J29_TAKRU Unreviewed; 338 AA.
AC Q50J29;
DT 07-JUN-2005, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2005, sequence version 1.
DT 24-JAN-2024, entry version 76.
DE SubName: Full=CMP-sialic acid transporter {ECO:0000313|EMBL:CAG29225.1};
DE Flags: Fragment;
GN Name=slc35a1 {ECO:0000313|EMBL:CAG29225.1};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|EMBL:CAG29225.1};
RN [1] {ECO:0000313|EMBL:CAG29225.1}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann F.;
RT "Evolution of sialic acids.";
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. SLC35A
CC subfamily. {ECO:0000256|ARBA:ARBA00009976}.
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DR EMBL; AJ705103; CAG29225.1; -; mRNA.
DR RefSeq; XP_003971879.1; XM_003971830.2.
DR AlphaFoldDB; Q50J29; -.
DR STRING; 31033.ENSTRUP00000051032; -.
DR GeneID; 777968; -.
DR KEGG; tru:777968; -.
DR CTD; 10559; -.
DR OrthoDB; 200085at2759; -.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015165; F:pyrimidine nucleotide-sugar transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR007271; Nuc_sug_transpt.
DR NCBIfam; TIGR00803; nst; 1.
DR PANTHER; PTHR10231:SF66; CMP-SIALIC ACID TRANSPORTER; 1.
DR PANTHER; PTHR10231; NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER; 1.
DR Pfam; PF04142; Nuc_sug_transp; 1.
DR PIRSF; PIRSF005799; UDP-gal_transpt; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 2: Evidence at transcript level;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022597}.
FT TRANSMEM 12..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 338
FT /evidence="ECO:0000313|EMBL:CAG29225.1"
SQ SEQUENCE 338 AA; 36911 MW; E5616C06F32169EE CRC64;
MAAENVSVVF KLYCLTVMTL VAATYTVALR YTRTIPSGDL YFSTTAVCIT EVVKLILSLG
MLIKETGSPV RLKNAIVEHV FCSPKELLKL SVPSVVYAVQ NNMAFLALSN LDAAVYQVTY
QLKIPCTALC TVLMLNRSLS RLQWFSVFVL CGGVILVQWK PAEASKVLVE QNPLVGFVAI
AVAVLCSGFA GVYFEKVLKS SDTSLWVRNI QMYLSGIVVT LIGVYVNDGE KVLEKGFFFG
YTSWVCFVVF LASVGGLYTS VVVKYTDNIM KGFSAAAAIV LSTVASVILF GLQITLSFAS
GAILVCVSIY LYGLPKQDTS KLRRQDLPHD SKEKLIMV
//
