ID Q54DF3_DICDI Unreviewed; 933 AA.
AC Q54DF3;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 24-JAN-2024, entry version 103.
DE RecName: Full=UBR-type domain-containing protein {ECO:0000259|PROSITE:PS51157};
GN ORFNames=DDB_G0292302 {ECO:0000313|EMBL:EAL61275.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL61275.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL61275.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL61275.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL61275.1}.
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DR EMBL; AAFI02000189; EAL61275.1; -; Genomic_DNA.
DR RefSeq; XP_629688.1; XM_629686.1.
DR AlphaFoldDB; Q54DF3; -.
DR SMR; Q54DF3; -.
DR STRING; 44689.Q54DF3; -.
DR PaxDb; 44689-DDB0184314; -.
DR GeneID; 8628604; -.
DR KEGG; ddi:DDB_G0292302; -.
DR dictyBase; DDB_G0292302; -.
DR eggNOG; KOG1777; Eukaryota.
DR HOGENOM; CLU_313862_0_0_1; -.
DR InParanoid; Q54DF3; -.
DR OMA; NQIFGQK; -.
DR PhylomeDB; Q54DF3; -.
DR Reactome; R-DDI-8951664; Neddylation.
DR Reactome; R-DDI-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR Proteomes; UP000002195; Chromosome 6.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR CDD; cd19671; UBR-box_UBR4_5_6_7; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 2.
DR InterPro; IPR039448; Beta_helix.
DR InterPro; IPR006633; Carb-bd_sugar_hydrolysis-dom.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR007742; NosD_dom.
DR InterPro; IPR022441; Para_beta_helix_rpt-2.
DR InterPro; IPR006626; PbH1.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR003126; Znf_UBR.
DR NCBIfam; TIGR03804; para_beta_helix; 1.
DR PANTHER; PTHR22990; F-BOX ONLY PROTEIN; 1.
DR PANTHER; PTHR22990:SF15; F-BOX ONLY PROTEIN 10; 1.
DR Pfam; PF13229; Beta_helix; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF05048; NosD; 1.
DR SMART; SM00722; CASH; 2.
DR SMART; SM00710; PbH1; 11.
DR SMART; SM00396; ZnF_UBR1; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF51126; Pectin lyase-like; 2.
DR PROSITE; PS51157; ZF_UBR; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 826..901
FT /note="UBR-type"
FT /evidence="ECO:0000259|PROSITE:PS51157"
FT ZN_FING 826..901
FT /note="UBR-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00508"
FT REGION 24..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 118..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 933 AA; 103664 MW; 586D628FC4F3AD3A CRC64;
MSTENIFSEF TFDRYCKKIK FDQQKRQDPL YSNINSQGEE EEEEDQEEQL VQQLEEEEQQ
QEEELNIQIN NLSNCNIKSN TSTPTRKRKI YNIIINDQDN ISDNINNTNN NYNTNLSNIN
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNDQ IMTIGYFSAE ETQQIVNTNT
ATTSTSSSSS GGNTTTNNNN NNSNNINMNT ANSSSNDTLN GDGEIATFDK SLDFKTATEN
LIESMQLSNL QSGSTSGGST SGSIRHPHCV HSGGSGISGS SSGSGGGMIG SNINSSNGTG
NLILNNNSNG LSDEYWILIF HFLDFKTLVA LSETCHLFYR LSNDRFLWES LLKKDRKKVI
LLPPGIDLTC PSSIYKSRRD YDTIVEALSQ LTEAKRETIL LAPSIYQENI SIDKPVDIIG
EGPLGGVVIE SSTGNTVSIS APYGSITNVA MRQHGHWFCI DIEKGSFSIS KCDITNLTLS
AIKIGRSASP WIANNIVHDC KEAGIAIFGG EGTIIGNHFT RNRYGSIEIV YSTSKPTIKL
NKIYKNKGYG IHVHTNATAF ISENIIEENE SDGISCWGGA SPIVSNNKIC NNLEDGIYIH
EDGKGIYEYN QIFGQKLDGI RISKSNPQIS HNTIHHNQGD GIRLVIRANP IITENHICEN
KRVGIHIYRE GMGIISNNYI YGNKNAGMQV YSRANATICN NKIVQNRCSG IYVSDYAIVN
IKGNEITNNG EVGVEIVSGA KALCFESNNI NRNWEGGLAY YMDSKPIGYE LSNSFQNNGQ
SGQQQFIMRQ GREIMAMYNN SSGKKSGNNK DLEPISFLVE NALQESMCTL SFTREYYHAQ
YWYECKTCSE PRKILGKSEI AVCEECAKKC HAGHDIGVRK YGHFYCDCGQ QLTSPCSCMK
PSESNNKNNL PTPYTHPIHR THQNLQQHIT ILS
//
