ID Q54E68_DICDI Unreviewed; 447 AA.
AC Q54E68;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 24-JAN-2024, entry version 86.
DE RecName: Full=UNC93-like protein MFSD11 {ECO:0000256|ARBA:ARBA00040302};
DE AltName: Full=Major facilitator superfamily domain-containing protein 11 {ECO:0000256|ARBA:ARBA00041910};
GN ORFNames=DDB_G0291722 {ECO:0000313|EMBL:EAL61557.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL61557.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL61557.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL61557.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL61557.1}.
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DR EMBL; AAFI02000182; EAL61557.1; -; Genomic_DNA.
DR RefSeq; XP_629994.1; XM_629992.1.
DR AlphaFoldDB; Q54E68; -.
DR PaxDb; 44689-DDB0184030; -.
DR GeneID; 8628324; -.
DR KEGG; ddi:DDB_G0291722; -.
DR dictyBase; DDB_G0291722; -.
DR eggNOG; KOG3098; Eukaryota.
DR HOGENOM; CLU_025356_2_0_1; -.
DR InParanoid; Q54E68; -.
DR OMA; QFQDKTH; -.
DR PhylomeDB; Q54E68; -.
DR Proteomes; UP000002195; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055075; P:potassium ion homeostasis; IEA:InterPro.
DR CDD; cd17338; MFS_unc93_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR010291; Ion_channel_UNC-93.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR044771; UN933_plant.
DR PANTHER; PTHR23294; ET TRANSLATION PRODUCT-RELATED; 1.
DR PANTHER; PTHR23294:SF0; UNC93-LIKE PROTEIN MFSD11; 1.
DR Pfam; PF05978; UNC-93; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 447 AA; 49482 MW; D17048CDBC87C25E CRC64;
MKNKEDLLQT PLLNDHHHQE ENDYYSHSKS IQNKNNNKIN IIILGLCFCI LFSAFSPTQI
LQTTINQNLG YYTLAVLYSS LSISNFISPF IVSKFGEKIS LIIGTLSYAI YIGSNIYVTQ
PSLYISSILV GFGGAILWNA QGSLIIKYST EETIGANTGL FFALFQTDQI IGNIGSATLI
NKAGLSNSIL FTIFMGISLM PIIGFLFLKC PITPKIKKTI KSINIQDEET KGNQENHDDD
DLSIKNIFKS IIILFKDKPI QLLIPSLLYS GISQTFFFGV FPSLIGVEWV GYVMSVFGFF
DALSSFILGK LSFKIGRKIL ILISTISSII GTVLIILVNQ SKIIYFSINN NNNYGEYKIL
CYFIGSALLG FSDAGFNTQL YSLLGVLYPT NGEAAVGVFK FVQSTATAVA FIYGPYASLF
ENVFVLDCLV IISCVFFIFA DNFSKSV
//
