GenomeNet

Database: UniProt
Entry: Q54Q80
LinkDB: Q54Q80
Original site: Q54Q80 
ID   Y4059_DICDI             Reviewed;        1280 AA.
AC   Q54Q80;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   23-MAY-2018, entry version 78.
DE   RecName: Full=SET and MYND domain-containing protein DDB_G0284059;
DE            EC=2.1.1.-;
GN   ORFNames=DDB_G0284059;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Mycetozoa; Dictyostelids; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A.,
RA   Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q.,
RA   Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F.,
RA   Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P.,
RA   Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P.,
RA   Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N.,
RA   Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M.,
RA   Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I.,
RA   Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R.,
RA   Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C.,
RA   Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D.,
RA   Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S.,
RA   Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T.,
RA   Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A.,
RA   Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M.,
RA   Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G.,
RA   Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Probable methyltransferase. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding
CC       methyltransferase superfamily. {ECO:0000255|PROSITE-
CC       ProRule:PRU00190}.
DR   EMBL; AAFI02000063; EAL65370.1; -; Genomic_DNA.
DR   RefSeq; XP_638717.1; XM_633625.1.
DR   ProteinModelPortal; Q54Q80; -.
DR   SMR; Q54Q80; -.
DR   STRING; 44689.DDB0238659; -.
DR   PaxDb; Q54Q80; -.
DR   PRIDE; Q54Q80; -.
DR   EnsemblProtists; EAL65370; EAL65370; DDB_G0284059.
DR   GeneID; 8624387; -.
DR   KEGG; ddi:DDB_G0284059; -.
DR   dictyBase; DDB_G0284059; -.
DR   eggNOG; KOG2084; Eukaryota.
DR   eggNOG; COG2940; LUCA.
DR   InParanoid; Q54Q80; -.
DR   OMA; YRRGICY; -.
DR   PRO; PR:Q54Q80; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   Proteomes; UP000002195; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR002893; Znf_MYND.
DR   Pfam; PF00856; SET; 1.
DR   Pfam; PF01753; zf-MYND; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50280; SET; 1.
DR   PROSITE; PS01360; ZF_MYND_1; 1.
DR   PROSITE; PS50865; ZF_MYND_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Complete proteome; Metal-binding; Methyltransferase;
KW   Reference proteome; Repeat; S-adenosyl-L-methionine; TPR repeat;
KW   Transferase; Zinc; Zinc-finger.
FT   CHAIN         1   1280       SET and MYND domain-containing protein
FT                                DDB_G0284059.
FT                                /FTId=PRO_0000389436.
FT   REPEAT      272    305       TPR 1.
FT   REPEAT      383    416       TPR 2.
FT   DOMAIN      822    965       SET. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00190}.
FT   REPEAT     1218   1251       TPR 3.
FT   ZN_FING     533    572       MYND-type. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00134}.
FT   COILED      439    468       {ECO:0000255}.
FT   COMPBIAS     16     22       Poly-Asn.
FT   COMPBIAS     23     42       His-rich.
FT   COMPBIAS    141    152       Poly-Gln.
FT   COMPBIAS    307    310       Poly-Ala.
FT   COMPBIAS    321    324       Poly-Gly.
FT   COMPBIAS    461    468       Poly-Gln.
FT   COMPBIAS    611    618       Poly-Gln.
FT   COMPBIAS    665    685       Poly-Thr.
FT   COMPBIAS    712    722       Poly-Ser.
FT   COMPBIAS    723    727       Poly-Thr.
FT   COMPBIAS    847    863       Poly-Gln.
FT   COMPBIAS   1042   1054       Poly-Gln.
FT   COMPBIAS   1070   1074       Poly-Asn.
SQ   SEQUENCE   1280 AA;  144701 MW;  F2B9427767308688 CRC64;
     MTKKIKLSNS ESNKVNNNNN NNHGNGHNHN HSHNHGEMCH GHGIIGIVDS VTGENIIQVN
     GENLRSVPNG HSLIHNINSI INSHSKHGKI KNILKDSTII SSSINLSDKP INKITEENSP
     PSSPTLSSST NTTTDRQELP QQQQQPQQQQ SQPSTPPPQQ QTNQKQQPEF NRYQANDILF
     RNKLTRSLSR NIPPLSLLKQ NFKDEMENSF HTAISNIKDL NEKVEMVNLI FQHNLSENNA
     MVNVDSIIHS STSGLLSEYK QITETFDWEQ TSKGYKNKGN ELFQKKQYSD ALLLYNESLR
     IYDMELAAAA TSTNLNEKEN GGGGNVGGSA TATATTINTP DVSILSSIHS NRCLCLVNLE
     RYKEGAIEAT RGIDLVGSSS VLHKLYYRRG ICYYHLRKHY KAKKDFLRAH TLIEKRDSSD
     LASIENYLFK IQKLSLPLQK DEEIEQELDN KNNNSNDDEK QQQQQQQQDI DVTISSILEK
     SESLIDSRVE FLYQSDLVGR ISEASDFIPS NTVLYQEEPY VSCLDRNYHS QYCYNCFKEI
     LSPIYCKECS NSQYCSNKCL NEDYVKQHGR ECGKGFLIIC SHESLLVIRL LARKGRDYRE
     ANKGKKEEEP QQQQQKQQKS RKLPNLTFIP KPNPTQIDQN LNKPKIVLPE PTTAAINTAL
     SSASTPTTAT ATTTTTTTTA TTPTTLAETL SSTSLTENKS DSTPPPTPLP PSSSSSSSSS
     SSTTTTTFSF NMSELQNLQI SQDDELFDVP TDPALFGKSN TYSQSYELIN SFNPHFEHHS
     NDSMANMIFD AFVIERFLLY YQKDLGILSE DIDVHVILRH LCQLTTYTFA IPGYIDNHDS
     LVLKTLQLQQ QQQQQQQQQQ NQQSNQQPNQ QSNQQSNQQS NQQSQPNQSP IIQSQNPPHA
     SPFSPLRYSV QKYSQDKIGY AVYPMASLMN HSCDNNTHLQ YDGCSLTIKS LFNIEKGEEI
     LGCYGPHAFL NPLKDRLINL YNEFFFVCRC KACSEKSGPD PIKCPGSYHD HLNSPESSPV
     ECSGTLLESI NMNQLVTMAK LQQQQQQQQQ HQQQNDKKKF NSNPTNLGSN NNNNYLNNNF
     NNPLRNGNPF LLKQTYDRYD DHEHRYFCCS KCGIELNGFD SFSLTSQIII SDNLFEMGFK
     AMTLYGNLSK DIETMLLRAL ELRKSIFKPC SKKIGDIYDS LSRFSISRED GASAAKYLEL
     LIENVISRLG HSNSADLGRE YSKLGQIYLT LGEIEKSEDA IEKAESILMS WKSNDPTDEE
     VLFLLTNRRK LFTAAHLINK
//
DBGET integrated database retrieval system