GenomeNet

Database: UniProt
Entry: Q54T74
LinkDB: Q54T74
Original site: Q54T74 
ID   SLRA_DICDI              Reviewed;        1378 AA.
AC   Q54T74;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   23-MAY-2018, entry version 70.
DE   RecName: Full=S-cell enriched with leucine-rich repeat-containing protein slrA;
GN   Name=slrA; ORFNames=DDB_G0282069;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Mycetozoa; Dictyostelids; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A.,
RA   Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q.,
RA   Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F.,
RA   Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P.,
RA   Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P.,
RA   Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N.,
RA   Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M.,
RA   Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I.,
RA   Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R.,
RA   Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C.,
RA   Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D.,
RA   Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S.,
RA   Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T.,
RA   Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A.,
RA   Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M.,
RA   Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G.,
RA   Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   DEVELOPMENTAL STAGE.
RX   PubMed=17673666; DOI=10.1126/science.1143991;
RA   Chen G., Zhuchenko O., Kuspa A.;
RT   "Immune-like phagocyte activity in the social amoeba.";
RL   Science 317:678-681(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Only expressed in sentinel 'S-cells'.
CC       {ECO:0000269|PubMed:17673666}.
DR   EMBL; AAFI02000044; EAL66456.1; -; Genomic_DNA.
DR   RefSeq; XP_640377.1; XM_635285.1.
DR   ProteinModelPortal; Q54T74; -.
DR   STRING; 44689.DDB0232377; -.
DR   PaxDb; Q54T74; -.
DR   PRIDE; Q54T74; -.
DR   EnsemblProtists; EAL66456; EAL66456; DDB_G0282069.
DR   GeneID; 8623330; -.
DR   KEGG; ddi:DDB_G0282069; -.
DR   dictyBase; DDB_G0282069; slrA.
DR   eggNOG; KOG0619; Eukaryota.
DR   eggNOG; COG4886; LUCA.
DR   InParanoid; Q54T74; -.
DR   OMA; CECYPNL; -.
DR   PRO; PR:Q54T74; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   Proteomes; UP000002195; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.10.10; -; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PROSITE; PS51450; LRR; 6.
PE   2: Evidence at transcript level;
KW   Coiled coil; Complete proteome; Glycoprotein; Leucine-rich repeat;
KW   Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN         1   1378       S-cell enriched with leucine-rich repeat-
FT                                containing protein slrA.
FT                                /FTId=PRO_0000391769.
FT   TRANSMEM     17     37       Helical. {ECO:0000255}.
FT   TRANSMEM   1160   1180       Helical. {ECO:0000255}.
FT   REPEAT      143    165       LRR 1.
FT   REPEAT      167    188       LRR 2.
FT   REPEAT      191    212       LRR 3.
FT   REPEAT      213    235       LRR 4.
FT   REPEAT      236    257       LRR 5.
FT   REPEAT      260    281       LRR 6.
FT   REPEAT      282    304       LRR 7.
FT   REPEAT      307    329       LRR 8.
FT   REPEAT      331    353       LRR 9.
FT   COILED      886    946       {ECO:0000255}.
FT   COMPBIAS    732    741       Poly-Asn.
FT   COMPBIAS    747    751       Poly-Asn.
FT   COMPBIAS    888    907       Poly-Asn.
FT   COMPBIAS    929    945       Poly-Asn.
FT   COMPBIAS   1229   1263       Poly-Asn.
FT   COMPBIAS   1270   1273       Poly-Asn.
FT   COMPBIAS   1307   1318       Poly-Asp.
FT   CARBOHYD     59     59       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    112    112       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    143    143       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    172    172       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    201    201       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    265    265       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    287    287       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    296    296       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    416    416       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    436    436       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    451    451       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    491    491       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    513    513       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    596    596       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    605    605       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    634    634       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    704    704       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    710    710       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    740    740       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    741    741       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    771    771       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    788    788       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    801    801       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    826    826       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    843    843       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    861    861       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    875    875       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    907    907       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    953    953       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    970    970       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD   1090   1090       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD   1100   1100       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD   1331   1331       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD   1360   1360       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
SQ   SEQUENCE   1378 AA;  156164 MW;  B686F2C4DCF7EF33 CRC64;
     MVKNQIFSLK SLWSSSIFKI LYCYLFTSLL LILSTWVSVN DGLSVREHII LLRLYFDTNG
     TTWYHNQGWK EYADCILAAD GSVRKALESI DPLTGQIPQY LWADHFSQLD NNKTLYKIIH
     NQIQGHKVVI CNAFGITCED RINLTGIDLS NNNLKGNITP YLPYLLHLRN LNLSNNHLSG
     CFPDGLLKAQ SLVALDLSYN NISCTLSLAD SKAISYIDIS HNHLTGYFKN VWKTPNLLFL
     DLSFNKLYGT ILKEFFRQKS LDYVNLSSNQ LIGFLPILSK SRISYLNISN NRLIGNITLL
     TCWKAGSLRI FDAENNMFEG ALPESIFDHS PLQYVNLKGN IVKDPLPSIL DCAKSEVKII
     VPDGLKQNKC DPKVSSNWVL ILNPLGEEFN IVGSDFGINS KSINIQFQNG LHCVDNVTTI
     IKSNTIISCK NPQGRNSTYL KLTIPTGEPG NFTVIKQQLY YYRPIIKSCS KVYKNIGGEI
     TILGSHLESF NKTSNGKKMI TVSIGNIKNS FTNVTSSINS DGFSGEVISC RNADIITPDM
     ITCSIPSNTN LQQPAEIQII IDGITAYVPI DSTRPHFLYK GVYNKDITIS KPTEYNQTIT
     ISVPNETIID MDQVVRVLID DNDDSICKNI QHINKTSIQC LPYSETCGSN VKVTLVTKYG
     EPQFTTSLNY PPPIITRVTQ GIDSTSNSII TINGKFLKTG GKRNLSIKIN DTICCPLYNE
     YYYKQDELDD DNNNNNNNNN NSTTDINNNN NIIKNNNLIK EEQILCYYQI NQSLPIHLNL
     PVTLTLSNQT VVKNNIYSQT NSTCPNNCVK HRTNGCRSGI CECYPNLTGP SCDENIPEST
     ISNFSNYLPD FILSFPKFIT NNTFNIKFLS ISEVNESGNI VDRFCSLNNN NNNNNNNNNK
     NNNNNNNDSN NEKEVVEDEE EDLDYSSQND NNNINNNNNE NNNENKLNWK LINQTKTTNA
     LYTLKIKKKN VTLDILISSD NNQHREVYFA GEVIQVPKSS IELIVNLKGK WLFKDPKNQL
     KFNFLVKPVN DHDYSLCLPS PFVLISDEPF RWITMDVDSS TIFAKPSNRF LLNNYLVRVI
     EPNYKLSDSN LTLNLYYQFN QTTLKQQDNH GDDNSDNSIK YTEDSLKFRI DFSTFNSRRE
     INPKPRGCFK DNTHKFPYDY YIVFFGCASG LILVLVICIV QCSRIESRQR KQIIKSFKAT
     QKMPVEIKTP LLPPSFHFNF LDYNNMDLNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     NFNDGSDTFN NNNKKNLNYE DNCDTVGFDG KENDIKNINN KKDEKEDDGD DDDDEDDDEY
     EDDTQPCSSG NSSRSKGSDG GSSSNSLSSD KQSFNNGNEN NSIIPENKKK HLTIINKK
//
DBGET integrated database retrieval system