ID Y1436_DICDI Reviewed; 200 AA.
AC Q556P3; Q86JY5;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-JAN-2010, sequence version 2.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Glutathione S-transferase domain-containing protein DDB_G0273153/DDB_G0273923;
GN ORFNames=DDB_G0273153;
GN and
GN ORFNames=DDB_G0273923;
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SIMILARITY: Belongs to the GST superfamily. {ECO:0000305}.
CC -!- CAUTION: The gene for this protein is duplicated in strains AX3 and
CC AX4. These strains contain a duplication of a segment of 750 kb of
CC chromosome 2 compared to the corresponding sequence in strain AX2.
CC {ECO:0000305}.
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DR EMBL; AAFI02000011; EAL70652.2; -; Genomic_DNA.
DR EMBL; AAFI02000009; EAL70794.2; -; Genomic_DNA.
DR RefSeq; XP_644578.3; XM_639486.2.
DR RefSeq; XP_644673.4; XM_639581.2.
DR AlphaFoldDB; Q556P3; -.
DR SMR; Q556P3; -.
DR STRING; 44689.Q556P3; -.
DR PaxDb; 44689-DDB0305017; -.
DR GeneID; 8618767; -.
DR GeneID; 8619209; -.
DR KEGG; ddi:DDB_G0273153; -.
DR KEGG; ddi:DDB_G0273923; -.
DR dictyBase; DDB_G0273153; -.
DR dictyBase; DDB_G0273923; -.
DR eggNOG; KOG1695; Eukaryota.
DR HOGENOM; CLU_039475_1_0_1; -.
DR InParanoid; Q556P3; -.
DR OMA; IKHEINQ; -.
DR PhylomeDB; Q556P3; -.
DR Reactome; R-DDI-156590; Glutathione conjugation.
DR Reactome; R-DDI-2162123; Synthesis of Prostaglandins (PG) and Thromboxanes (TX).
DR PRO; PR:Q556P3; -.
DR Proteomes; UP000002195; Chromosome 2.
DR Gene3D; 1.20.1050.130; -; 1.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR004046; GST_C.
DR PANTHER; PTHR11571; GLUTATHIONE S-TRANSFERASE; 1.
DR PANTHER; PTHR11571:SF116; GLUTATHIONE S-TRANSFERASE DOMAIN-CONTAINING PROTEIN DDB_G0273153_DDB_G0273923; 1.
DR Pfam; PF14497; GST_C_3; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR PROSITE; PS50405; GST_CTER; 1.
DR PROSITE; PS50404; GST_NTER; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..200
FT /note="Glutathione S-transferase domain-containing protein
FT DDB_G0273153/DDB_G0273923"
FT /id="PRO_0000350743"
FT DOMAIN 1..71
FT /note="GST N-terminal"
FT DOMAIN 73..195
FT /note="GST C-terminal"
SQ SEQUENCE 200 AA; 23232 MW; 7DE05441AE1AB373 CRC64;
MISSIYIFKI LLSYLGVEYE INQLSEINQE FTNKLESYNQ FIKHTQKDED YLLGQSAVIS
RYISNNHNFS GKSLQESARV DDIVESVLEI IEEYVLPIIN SNIINEEITK LLCTHFNDFE
NQLSKSTFSA GDSTTLADLY LFILYDITLR YLENHGHLAH HFNEKYPHLE RLKLHFLSNK
SVSEFINSNN INSQSSQLII
//
