ID Q557A4_DICDI Unreviewed; 655 AA.
AC Q557A4; Q86JS1;
DT 02-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 02-MAY-2006, sequence version 1.
DT 24-JAN-2024, entry version 103.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAL70539.1};
GN Name=aslC-2 {ECO:0000313|EMBL:EAL70539.1};
GN Synonyms=aslC-1 {ECO:0000313|EMBL:EAL70830.1};
GN ORFNames=DDB_G0273225 {ECO:0000313|EMBL:EAL70830.1}, DDB_G0273697
GN {ECO:0000313|EMBL:EAL70539.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL70539.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL70539.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL70539.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=12097910; DOI=10.1038/nature00847;
RG Dictyostelium Genome Sequencing Consortium;
RA Glockner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2] {ECO:0000313|EMBL:EAL70539.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL70539.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [3] {ECO:0000313|EMBL:EAL70539.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL70539.1};
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.-A., Sucgang R.,
RA Song J., Cox E.C., Tunggal B., Szafranski K., Konfortov B.A.,
RA Farbrother P., Bankier A.T., Lehmann R., Hamlin N., Xu Q., Davies R.,
RA Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.,
RA Davis P., Nie X., Kerhornou A., Hemphill L., Bason N., Berriman M.,
RA Desany B., Churcher C., Cooper J., van Driessche N., Cronin A.,
RA Goodhead I., Muzny D., Hall N., Harper D., Lindsay R., Hauser H., James K.,
RA Quiles M., Buchrieser C., Wardroper A., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Price C., Ma J., Quail M.,
RA Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Weinstock G.,
RA Sharp S., Just E., Shaulsky G., Simmonds M., Tivey A., White B., Walker D.,
RA Woodward J., Winckler T., Schleicher M., Rosenthal A., Rivero F.,
RA Chisholm R.L., Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J.,
RA Dear P.H., Noegel A.A., Barrell B., Kuspa A.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL70539.1}.
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DR EMBL; AAFI02000011; EAL70539.1; -; Genomic_DNA.
DR EMBL; AAFI02000009; EAL70830.1; -; Genomic_DNA.
DR RefSeq; XP_644465.1; XM_639373.1.
DR RefSeq; XP_644785.1; XM_639693.1.
DR AlphaFoldDB; Q557A4; -.
DR SMR; Q557A4; -.
DR STRING; 44689.Q557A4; -.
DR PaxDb; 44689-DDB0231690; -.
DR GeneID; 8618887; -.
DR GeneID; 8619090; -.
DR KEGG; ddi:DDB_G0273225; -.
DR KEGG; ddi:DDB_G0273697; -.
DR dictyBase; DDB_G0273225; aslC-1.
DR dictyBase; DDB_G0273697; aslC-2.
DR eggNOG; KOG1175; Eukaryota.
DR HOGENOM; CLU_000022_3_5_1; -.
DR OMA; PRDTYFC; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IBA:GO_Central.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347:SF4; ACETYL-COA SYNETHETASE-RELATED; 1.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002195}.
FT DOMAIN 16..64
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 74..465
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 530..617
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 655 AA; 75068 MW; 3AE7CD838776E2F8 CRC64;
MYRLSEPFDY LNDKTYANNE PEAFWDEVAK KLIKWDKMYD KVYSGDEMYP DWFKGGELNT
CYNVLDRQVQ NPLKRDQDAL IYECPYLKKT VKLTYYQLYE KVCEFSRVLL NLNISKNDNV
LIYMANTLEP LIAMLSCARI GATHCTIFDG YSVKSLIDRI ETITPKLIIT TNYGILNDEI
ITFTPNLKDA IEQSTFKPSN VITLFRNDIT SESDLKKVKD IPTIPNTLSW YDEIKKFKEN
NQSPFYEYVP VESSHPLYII YTSGTTGNSK AVVRSNGSHM VCLNYFNRYI SENNQSTTLL
TTSSVGWVSF HGFLYGMLSF GSTFVMYEGG IIKNKHIEVD LWNTIEKHKV THALSLASAI
RYLIKTDPEG TILRSKYDLS NLKEIWIGGE PIEESISEYI EQKLKIKSTR GYGQTEIGIT
YLYCFGHINI PYYATGLPSI FIRPSIFSDD GKELGVNEIG EIAFKLPMPP SFATTFYKND
EKFKQLFSKF PGYYNPGDLG FKDENGFYTI VSRSDDQIKI SGNKVQLNTI ETSILKHPSV
LECCSIGIND PTCYSVPIAL LVLKQQQQQQ QDQSTRQIDL NKLHSEINNI ITQDIASLAV
LRKIVIVNQL PKTKTGKIPR PIISKFLNDS NFLLPDNISN VEIFYEIKEL YTKIN
//
