ID   VAPA_DICNO              Reviewed;         102 AA.
AC   Q57475;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   RecName: Full=Virulence-associated protein A;
GN   Name=vapA;
OS   Dichelobacter nodosus (Bacteroides nodosus).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Cardiobacteriales;
OC   Cardiobacteriaceae; Dichelobacter.
OX   NCBI_TaxID=870;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=A198;
RX   PubMed=1398971; DOI=10.1128/iai.60.11.4586-4592.1992;
RA   Katz M.E., Rood J.I., Strugnell R.A.;
RT   "Molecular characterization of a genomic region associated with virulence
RT   in Dichelobacter nodosus.";
RL   Infect. Immun. 60:4586-4592(1992).
CC   -!- SIMILARITY: Belongs to the VapA/VapI family. {ECO:0000305}.
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DR   EMBL; L31763; AAB00943.1; -; Genomic_DNA.
DR   EMBL; L22308; AAA20207.1; -; Unassigned_DNA.
DR   EMBL; M74565; AAA23351.1; -; Genomic_DNA.
DR   PIR; D49205; D49205.
DR   RefSeq; WP_012030621.1; NZ_SRJB01000012.1.
DR   AlphaFoldDB; Q57475; -.
DR   SMR; Q57475; -.
DR   OMA; NCHAAIS; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR013430; Toxin_antidote_HigA.
DR   NCBIfam; TIGR02607; antidote_HigA; 1.
DR   PANTHER; PTHR36924; ANTITOXIN HIGA-1; 1.
DR   PANTHER; PTHR36924:SF1; ANTITOXIN HIGA-1; 1.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Virulence.
FT   CHAIN           1..102
FT                   /note="Virulence-associated protein A"
FT                   /id="PRO_0000149742"
FT   DOMAIN          14..69
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        25..44
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
SQ   SEQUENCE   102 AA;  11266 MW;  8025D2B1CB78585E CRC64;
     MAKMKNPPHP GLMLKVMYLE PLGLNITETA EKLDMPRSAL SEIVNAKRAI SPEVAVKLEK
     AFPKHSASFW LRAQAGYALS RVNPHCADKV KPIKTSPLME SV
//