ID Q57VY9_TRYB2 Unreviewed; 1009 AA.
AC Q57VY9; D6XLI1;
DT 10-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2005, sequence version 1.
DT 24-JAN-2024, entry version 82.
DE RecName: Full=CH-like domain-containing protein {ECO:0000259|Pfam:PF06294};
GN Name=Tb08.29H22.870 {ECO:0000313|EMBL:AAZ13211.1};
GN ORFNames=Tb927.8.4460 {ECO:0000313|EMBL:AAX70230.1};
OS Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=185431 {ECO:0000313|EMBL:AAX70230.1, ECO:0000313|Proteomes:UP000008524};
RN [1] {ECO:0000313|EMBL:AAZ13211.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ13211.1};
RX PubMed=16020724; DOI=10.1126/science.1112181;
RA El-Sayed N.M., Myler P.J., Blandin G., Berriman M., Crabtree J.,
RA Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C.,
RA Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.N.,
RA Wortman J.R., Alsmark U.C., Angiuoli S., Anupama A., Badger J.,
RA Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T.,
RA Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C.,
RA Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J., Salzberg S.L.,
RA Shallom J., Silva J.C., Sundaram J., Westenberger S., White O.,
RA Melville S.E., Donelson J.E., Andersson B., Stuart K.D., Hall N.;
RT "Comparative genomics of trypanosomatid parasitic protozoa.";
RL Science 309:404-409(2005).
RN [2] {ECO:0000313|EMBL:AAZ13211.1, ECO:0000313|Proteomes:UP000008524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ13211.1,
RC ECO:0000313|Proteomes:UP000008524};
RX PubMed=16020726; DOI=10.1126/science.1112642;
RA Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT "The genome of the African trypanosome Trypanosoma brucei.";
RL Science 309:416-422(2005).
RN [3] {ECO:0000313|EMBL:AAX70230.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GUTat10.1 {ECO:0000313|EMBL:AAX70230.1};
RA Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L.,
RA Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J.,
RA Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G.,
RA Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O.,
RA Wortman J., Fraser C.M., El-Sayed N.M.A.;
RT ".";
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AAZ13211.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ13211.1};
RA Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L.,
RA Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J.,
RA Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G.,
RA Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O.,
RA Wortman J., Fraser C.M., El-Sayed N.M.A.;
RT "Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2
RT through 8.";
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AC159435; AAX70230.1; -; Genomic_DNA.
DR EMBL; CP000071; AAZ13211.1; -; Genomic_DNA.
DR RefSeq; XP_847277.1; XM_842184.1.
DR AlphaFoldDB; Q57VY9; -.
DR PaxDb; 5691-AAZ13211; -.
DR GeneID; 3659448; -.
DR KEGG; tbr:Tb927.8.4460; -.
DR VEuPathDB; TriTrypDB:Tb927.8.4460; -.
DR eggNOG; ENOG502QU8V; Eukaryota.
DR InParanoid; Q57VY9; -.
DR OMA; MHSYEDK; -.
DR OrthoDB; 313887at2759; -.
DR Proteomes; UP000008524; Chromosome 8.
DR GO; GO:0005930; C:axoneme; IDA:GeneDB.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0051493; P:regulation of cytoskeleton organization; IBA:GO_Central.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR010441; CH_2.
DR InterPro; IPR036872; CH_dom_sf.
DR PANTHER; PTHR12509; SPERMATOGENESIS-ASSOCIATED 4-RELATED; 1.
DR PANTHER; PTHR12509:SF8; SPERMATOGENESIS-ASSOCIATED PROTEIN 4; 1.
DR Pfam; PF06294; CH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008524}.
FT DOMAIN 17..111
FT /note="CH-like"
FT /evidence="ECO:0000259|Pfam:PF06294"
FT REGION 198..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 240..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 812..836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..836
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1009 AA; 109596 MW; E4AA61EF5BC9388C CRC64;
MLETHCQFKH EGLPREVLAW LRCLQLPRFL RFPRRDLSNG FLVATICSRY WKNISMHSYE
DKLSVVNKRN NWEQLKKHFQ QNNCPLSDRM IEGLIACREG YAESLLRQLY TLLTGREVLE
AAPLPAVEIT PPTVVHTSVA KKVDIEATAD HVEERKVQSN RVRGIMQRGF VPIQPMENEV
PPPAVDDASS RVLHSMAQDP ADEDVGSSGG GGAEGTERPP VAFSISMRRS EVQPTVVCAT
GGKAGRRSSR STRDVDPDLG DLGPTYTEEM SALNFIEGIV RSQGAGLKPP PSQLSKRSPG
IKIRDEAAYT SCFLSDETAV GTLLQCRVWS SLLSRVGDVA AIILRDGSNL SEVAALFLRE
PPKRAQRCQS VPGSPRGRNT SDLLKLTSSA ASASGQHASQ RYMFLASVMS NISDVDAFLA
VSLYRDDILH NAKEAMRRLD HIGADNHAAL LCSALPADRA IALKLLPDIV SHVYNVVTQQ
GGASARTSFL LFLAAVVTRV TRDARAGGGS ANKTQRMSSV LDSARSSAEL GLEDSLSETI
FTIAGYHVIG ALSHESTVVR LAGARLAEVL VSRGCSRELL IDTILPLLSS CCSIPTTPLF
TCVCVGWLRR ALQRLCGWTC DKTWSNCISP SGTVTVSPAS LVQADSFFDG EHRNLPDHVV
YQLAVIMRNI RQVLRRPGSA NLRLYIAEQL SLCLNDIPHQ NESQALLQPQ EVAVDVLRAL
KDAPEKAVES FFSPVLPPAV ASATTKWVQI PQSGPSLVQS PLIGSLLATG RLCDCYPLAL
SEAVLLLFPQ DELSGTEGSP GRIRLTRDVR RQNGGAAPTP SGASPGTVKN GSFRMSGGKK
QSVAYETTIN ENMAQRVTWL YKINVSCRSG NSFPERSANL PENISSRRWV AVFQAMYSDI
LALTNFSETI FSRKLAVTDE STNNIARLGG MAQQLVAAWH KEVCRDGLGS VGSRIGTGTQ
VQGRNQGSTL LDAMAWYNGL CRNGTLGKDR YGVDTPAAPL LGSSVKERT
//
