ID Q582B5_TRYB2 Unreviewed; 914 AA.
AC Q582B5; D6XGI8;
DT 10-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAX80454.1};
GN Name=Tb05.3C6.720 {ECO:0000313|EMBL:AAZ11365.1};
GN ORFNames=Tb927.5.2520 {ECO:0000313|EMBL:AAX80454.1};
OS Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=185431 {ECO:0000313|EMBL:AAX80454.1, ECO:0000313|Proteomes:UP000008524};
RN [1] {ECO:0000313|EMBL:AAX80454.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GUTat10.1 {ECO:0000313|EMBL:AAX80454.1};
RA El-Sayed N.M., Khalak H., Adams M.D.;
RL Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAZ11365.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ11365.1};
RX PubMed=16020724; DOI=10.1126/science.1112181;
RA El-Sayed N.M., Myler P.J., Blandin G., Berriman M., Crabtree J.,
RA Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C.,
RA Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.N.,
RA Wortman J.R., Alsmark U.C., Angiuoli S., Anupama A., Badger J.,
RA Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T.,
RA Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C.,
RA Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J., Salzberg S.L.,
RA Shallom J., Silva J.C., Sundaram J., Westenberger S., White O.,
RA Melville S.E., Donelson J.E., Andersson B., Stuart K.D., Hall N.;
RT "Comparative genomics of trypanosomatid parasitic protozoa.";
RL Science 309:404-409(2005).
RN [3] {ECO:0000313|EMBL:AAZ11365.1, ECO:0000313|Proteomes:UP000008524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ11365.1,
RC ECO:0000313|Proteomes:UP000008524};
RX PubMed=16020726; DOI=10.1126/science.1112642;
RA Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT "The genome of the African trypanosome Trypanosoma brucei.";
RL Science 309:416-422(2005).
RN [4] {ECO:0000313|EMBL:AAX80454.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GUTat10.1 {ECO:0000313|EMBL:AAX80454.1};
RA Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L.,
RA Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J.,
RA Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G.,
RA Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O.,
RA Wortman J., Fraser C.M., El-Sayed N.M.A.;
RT ".";
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:AAZ11365.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ11365.1};
RA Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L.,
RA Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J.,
RA Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G.,
RA Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O.,
RA Wortman J., Fraser C.M., El-Sayed N.M.A.;
RT "Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2
RT through 8.";
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AC091655; AAX80454.1; -; Genomic_DNA.
DR EMBL; CP000068; AAZ11365.1; -; Genomic_DNA.
DR RefSeq; XP_844924.1; XM_839831.1.
DR AlphaFoldDB; Q582B5; -.
DR STRING; 185431.Q582B5; -.
DR PaxDb; 5691-AAZ11365; -.
DR GeneID; 3657360; -.
DR KEGG; tbr:Tb927.5.2520; -.
DR VEuPathDB; TriTrypDB:Tb927.5.2520; -.
DR eggNOG; KOG1128; Eukaryota.
DR InParanoid; Q582B5; -.
DR OMA; HLWKAWE; -.
DR OrthoDB; 23605at2759; -.
DR Proteomes; UP000008524; Chromosome 5.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR044244; TTC27/Emw1.
DR PANTHER; PTHR16193:SF0; TETRATRICOPEPTIDE REPEAT PROTEIN 27; 1.
DR PANTHER; PTHR16193; UNCHARACTERIZED; 1.
DR Pfam; PF13432; TPR_16; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008524};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 503..536
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 667..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 914 AA; 104056 MW; 4A9F812365D52F04 CRC64;
MVPSIPQLLL ELPVVCVSEN HLLNGRLTLS VKDATATAQS YYGAVEKYLQ GREPHLDLEK
DVVPAIDFAL RLFNAENFSG ELVPAEREQL STVLDRYATV DTLHERYVQR LLMSDGEMPH
PCVRLSRMLL AVLATACSSV KHAGQSQPQP LLPYTSVWRL RCHMRHQLIM QHRAHSIFLH
LSSCVDAALA LPDESLTAEH LLEVGHVQNY YHQRELAAEV FWRAARKSGL SVSEDTMVGV
RTRWQQQRMV QMVVNASSQV PFAAPISESD ATGGDVPLAV MSEKDGHDLL DRPREAAEAP
VAELQALQPL DKAIMLALCI DIRNTNPYHG LTQHRMQTYV ERLLSDPVPA PFIIQCQTLL
LRARLERGRN RVQERAFMQM TELVDQHSAG RDPNRATFHR TDSDYFYSVA YPSIWQLRSE
YADFCFDESL VKTALDAYEQ VQDWENIIKC CKVLDKRRRA ESLARDLLES DPCNPLLWVA
LGEATREAEH LTKAWELSDH RSAAPMRALA RLALEREEYE RVVECFDEAV RLNPVFGGDW
FALGYAAMQL KRWERSGEAF TRVCQIQPND AYAWNNLASV LLRTGKLRPA FNAMNQALRN
NRRDWRMWQN YFAIGCELKE VTETTNALNV LLDIAQRNVH LERGSLNRFV ENAIAYMEGR
IPASCKDQQM TEEDQEQAVE QEAENRDEGG RMHRAAVTNT SATRMGVEDD SIATNGNHVN
PSDEDAMCDI VPLCADIDLP DMCSPSTNAA AAEEAERVRE GVISRYKFRL RETFKRIIDL
FVTDPDIYAC AAKLLRYMDG PLTAYEMRQK ELRCCQQKDQ WERDTARFAR TCECLNDMSR
DLLDAVDYCG DSVDNLKKNN IVTVLSDTVN NVIAALEASE EYMEETAEYK QLRGELLPRM
RKALKETKTR IMAD
//
