ID Q5A5C1_CANAL Unreviewed; 344 AA.
AC Q5A5C1; Q9UVI7;
DT 26-APR-2005, integrated into UniProtKB/TrEMBL.
DT 26-APR-2005, sequence version 1.
DT 24-JAN-2024, entry version 104.
DE SubName: Full=Glutamine amidotransferase subunit {ECO:0000313|EMBL:AOW30648.1};
GN Name=DUG3 {ECO:0000313|CGD:CAL0000185194,
GN ECO:0000313|EMBL:AOW30648.1};
GN OrderedLocusNames=CAALFM_C703020CA {ECO:0000313|EMBL:AOW30648.1},
GN orf19.12626 {ECO:0000313|CGD:CAL0000185194};
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561 {ECO:0000313|EMBL:AOW30648.1, ECO:0000313|Proteomes:UP000000559};
RN [1] {ECO:0000313|EMBL:AOW30648.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2] {ECO:0000313|EMBL:AOW30648.1, ECO:0000313|Proteomes:UP000000559}
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=17419877; DOI=.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3] {ECO:0000313|EMBL:AOW30648.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=24025428; DOI=.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
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DR EMBL; CP017629; AOW30648.1; -; Genomic_DNA.
DR RefSeq; XP_716981.1; XM_711888.2.
DR AlphaFoldDB; Q5A5C1; -.
DR SMR; Q5A5C1; -.
DR STRING; 237561.Q5A5C1; -.
DR EnsemblFungi; C7_03020C_A-T; C7_03020C_A-T-p1; C7_03020C_A.
DR GeneID; 3641381; -.
DR KEGG; cal:CAALFM_C703020CA; -.
DR CGD; CAL0000185194; DUG3.
DR VEuPathDB; FungiDB:C7_03020C_A; -.
DR eggNOG; KOG1268; Eukaryota.
DR HOGENOM; CLU_042555_4_0_1; -.
DR InParanoid; Q5A5C1; -.
DR OMA; SVHPAWN; -.
DR OrthoDB; 211603at2759; -.
DR Proteomes; UP000000559; Chromosome 7.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0061672; C:glutathione hydrolase complex; IBA:GO_Central.
DR GO; GO:0036374; F:glutathione hydrolase activity; IEA:EnsemblFungi.
DR GO; GO:0008242; F:omega peptidase activity; IBA:GO_Central.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006751; P:glutathione catabolic process; IBA:GO_Central.
DR CDD; cd01908; YafJ; 1.
DR Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 1.
DR InterPro; IPR026869; EgtC-like.
DR InterPro; IPR017932; GATase_2_dom.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR PANTHER; PTHR43187; GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED; 1.
DR PANTHER; PTHR43187:SF1; GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED; 1.
DR Pfam; PF13230; GATase_4; 1.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR PROSITE; PS51278; GATASE_TYPE_2; 1.
PE 4: Predicted;
KW Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962,
KW ECO:0000313|EMBL:AOW30648.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000559}.
FT DOMAIN 2..292
FT /note="Glutamine amidotransferase type-2"
FT /evidence="ECO:0000259|PROSITE:PS51278"
SQ SEQUENCE 344 AA; 38666 MW; A0ACC25D441DC464 CRC64;
MCRFMIYKGR EEMVLSDLLT KPAHSIINQS FDSRLRLDMR NPVNGDGFGV GYYSENRHPC
IFKAITPAWN NVNLNNLAEC TESSLVFAHV RASTQGVLAE TNCHPFSYGK IMFMHNGGVS
AFNLIKKKLI NHLEDKFFLH IQGSTDSECC FALFVDTLYK MGYDPEDLSV KFSHSILRKA
LLTTIDLIKT WQCQVTNEPS LLNFAATDGE SIVVSRYITS KTDEAASLHF STGSKFFEYQ
PGLFKMERLN RSQDVIFVSS EPLTFERGDW LCVPTNTILT ITNRNTVLMH PIEDEFYDGE
VQRSSGLAMS KGLIGGVPMK DVEVDSTLAE VPPLDREGRV AVNV
//
