ID Q5AUL1_EMENI Unreviewed; 1156 AA.
AC Q5AUL1; C8V5T5;
DT 26-APR-2005, integrated into UniProtKB/TrEMBL.
DT 26-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=Pfs, NACHT and Ankyrin domain protein (AFU_orthologue AFUA_1G01020) {ECO:0000313|EMBL:CBF73717.1};
GN ORFNames=ANIA_08019 {ECO:0000313|EMBL:CBF73717.1};
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321 {ECO:0000313|EMBL:CBF73717.1, ECO:0000313|Proteomes:UP000000560};
RN [1] {ECO:0000313|Proteomes:UP000000560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.J., Wortman J.R., Batzoglou S.,
RA Lee S.I., Basturkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M., Hynes M., Paoletti M., Fischer R., Miller B.,
RA Dyer P., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2] {ECO:0000313|Proteomes:UP000000560}
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
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DR EMBL; BN001302; CBF73717.1; -; Genomic_DNA.
DR RefSeq; XP_681288.1; XM_676196.1.
DR AlphaFoldDB; Q5AUL1; -.
DR EnsemblFungi; CBF73717; CBF73717; ANIA_08019.
DR GeneID; 2869102; -.
DR KEGG; ani:AN8019.2; -.
DR eggNOG; KOG0504; Eukaryota.
DR HOGENOM; CLU_000288_34_2_1; -.
DR InParanoid; Q5AUL1; -.
DR OMA; ATYEHES; -.
DR OrthoDB; 1837258at2759; -.
DR Proteomes; UP000000560; Chromosome II.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24166:SF48; ANKYRIN REPEAT DOMAIN 29; 1.
DR PANTHER; PTHR24166; ROLLING PEBBLES, ISOFORM B; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 4.
DR Pfam; PF01048; PNP_UDP_1; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 11.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 10.
DR PROSITE; PS50088; ANK_REPEAT; 10.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000000560};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 20..257
FT /note="Nucleoside phosphorylase"
FT /evidence="ECO:0000259|Pfam:PF01048"
FT REPEAT 796..828
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 829..861
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 862..894
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 895..927
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 928..960
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 961..993
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 994..1026
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1027..1059
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1060..1092
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1093..1125
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 1156 AA; 128686 MW; 47F985652722FCE4 CRC64;
MAAARAMLDK VHRDLHMSEG DSNTYTLGRI AQHNVVIACL PAEQYGTNNA ASIMTNMKRT
FPRIRAGLIV GIGGGVPGKA DVRLGDIVVG TRVMQYDLGK MVGDGQLHRT AFPRIPHQLL
GTAVSSLRAK HELEPSRVSS ILRQKLGANF EYNRPSLPDL LYEATYNHAS PAAGCDACDH
SKLVPRRKRA TDDVVIHYGA IASGNQVMKT AIIRDRIAQQ LDVICFEMEA AGLMDILPCL
PIRGICDYAD SHKSDGWQRY AAAVAAAYAR ELLEELPVAT SARSDYTPDD GRCSTHGMQH
ERRRRLLDSL KFDQIDSRKS TIKTEHAKTC RWFLSHPDYQ AWLDPEQLEQ NHGFLWISGK
PGAGKSTIMK FAYLNMKKKA RRMHAVTASF FFFNARGELL EKSILGMYRS LLLQLLEGYP
DLQAVLDDVD LVPPNQNDCP SLNSLKGLFC NAITALGQRP FTCFVDALDE CDEQQVADMV
LYFEDLAEKS TANGVPLRIC FSSRHYPYIA IRRGIRHTLE DQPGHAKDME TYVSSRLQIG
EPALREELQP QLLSKAAGVF MWVVLVVDIL NREYRRGGLA LRKRLAEIPG DLSELFRDIL
RRDNENMEDL LLCILWILYA NRPLQPKEFY HALWSGLTLK AVVAVSRQLA KTEPDGQMEI
PRKYPFLEYA TQHVLDHANT AAKSVPQDKF LSAFPVSDWV KASNLFEKKK VRRYSPDINL
FYLLAEKGLS ELIYTRLKDD QTVHVFGGRY KYPLFAALAN CKRDAAAALL MTRSRFCDGV
DITEGLNRRK DLKHYETRTP LSWAAQEGRA IIVKLLLQTG SSLNAVDLGG QTPLLRASKN
GHETVAKLLI DHGADLNATS KEGRTPLIQA SENGHEAVAR LLIDHGADVN ASERDGWTPL
IHASHKGHEA VARLLIDYGA DLNSKDRYGW TPLIQASQNG HEVVVRLLID HGADVNASNR
DGWTPLLRAT EHCHEAVVRL LIDHGADVNA SSIDGFTPLL RATELCHEAV VRLLIDHGAD
VNASERDGWT PLIHASHNGH EAVARLLIDH GADVNATGED GRTPLICALK NRHEAVVRLL
IDCGADVEAK GGYGWTPLIH ALQNNHEAVE ELLIDHGADI DASDEYERTL LVPALQNGHE
AVARLLVDKQ SRYQML
//
