ID Q5B570_EMENI Unreviewed; 978 AA.
AC Q5B570; C8V984;
DT 26-APR-2005, integrated into UniProtKB/TrEMBL.
DT 26-APR-2005, sequence version 1.
DT 24-JAN-2024, entry version 113.
DE SubName: Full=Cyclin dependent kinase inhibitor Pho81, putative (AFU_orthologue AFUA_4G06020) {ECO:0000313|EMBL:CBF77792.1};
GN ORFNames=ANIA_04310 {ECO:0000313|EMBL:CBF77792.1};
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321 {ECO:0000313|EMBL:CBF77792.1, ECO:0000313|Proteomes:UP000000560};
RN [1] {ECO:0000313|Proteomes:UP000000560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.J., Wortman J.R., Batzoglou S.,
RA Lee S.I., Basturkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M., Hynes M., Paoletti M., Fischer R., Miller B.,
RA Dyer P., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2] {ECO:0000313|Proteomes:UP000000560}
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
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DR EMBL; BN001303; CBF77792.1; -; Genomic_DNA.
DR RefSeq; XP_661914.1; XM_656822.1.
DR AlphaFoldDB; Q5B570; -.
DR STRING; 227321.Q5B570; -.
DR EnsemblFungi; CBF77792; CBF77792; ANIA_04310.
DR GeneID; 2872108; -.
DR KEGG; ani:AN4310.2; -.
DR eggNOG; KOG0504; Eukaryota.
DR eggNOG; KOG2421; Eukaryota.
DR HOGENOM; CLU_002842_1_0_1; -.
DR InParanoid; Q5B570; -.
DR OMA; LCTALNW; -.
DR OrthoDB; 4907at2759; -.
DR Proteomes; UP000000560; Chromosome III.
DR GO; GO:0047389; F:glycerophosphocholine phosphodiesterase activity; IBA:GO_Central.
DR GO; GO:0046475; P:glycerophospholipid catabolic process; IBA:GO_Central.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR22958:SF23; DEPENDENT KINASE INHIBITOR PHO81, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06020)-RELATED; 1.
DR PANTHER; PTHR22958; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF03009; GDPD; 1.
DR SMART; SM00248; ANK; 7.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS51704; GP_PDE; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000000560}.
FT REPEAT 273..306
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 372..405
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 407..439
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 659..964
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 978 AA; 109224 MW; 244C85E8EC3FA916 CRC64;
MLPKHRLHSV RTRRSFFSDW RPRSVPLSRT AAQKPDIRRQ FSQRLKTLVD KKRVAQSRTV
TKPKAPANLV ALLEGFQQFD GDLNKLQQFV EINETAMSKI LKKSRMKELY LHRAVEVQPC
FNRDVLRDLS DRATTARIEL EAWAEGENIQ FDTTRPTDRT TTFQGFGSEE EDLDLQVLQS
ANSGNLYALR EWADKLQKSG DSRERATRTF LAAISEYSDD VLAVLLETGL VDIFAEDDIN
ERNCLHEAAI SGREFVLKAG LEAGVQVSRT DVYGRIPLHY ACIHGRVGMV QQLLATDPST
VDIMDHDNFT PLIHSIVKNQ LDCAEQLLRN NARIDPVSES DHIPLNLACQ HGSLPIVKML
LERQARLLPD AEGLYPQHMV ARASQSPDIL LLLKRHGADL NQRDKLYQWT PLFHAASEGC
VNCLRTLLEL GVDADVKDEK GLAAVYYAAW EGHLECMLLL WSHHTESQPS QRPLDILNGL
RLHEPSSTIA WQEHTPAEAQ DMETVDGIPD LSLPPPIIPL RRYGHNFLDK KVFVQILFDP
GSSISFDQAG RYPAARLTIS SKLSELIPRT VMLPIQEDAR MISFHVDTLQ TFTVDFEIFP
TFGSKVIAKT VALPTVFGAE ESSAGSCCLP LFDPRLRAIG QLRFWFQVIK PYHGDPLEIT
HFATYWKATS TGESDHSGLV TGSSLSGDHV QLFVQLTRDK VPVVHPQYMV KHYGIDIPIC
HLTFSEFQAV GGEKNVNRPE LLQFLQAHAA DDLALTHRVL AASFLSLREV FENLPVDVNV
NISVLYPSAA EEQALKMTSM TDVNTFADAI LTVVFDHARV ARDKNPEFMR SVVFTSYNAN
ICVALNWKQP NYPVLLCNDL GQIRDLARNA GTHPDVDSSG RASMSIKESA RVAQSNNFMG
LICRSSLLNV VPALVATIKE LGLVLVADTS DEAEQPETQA LSAAGSMGVA ELAYRMPEGV
NGLMKANGIL RFNDMIDM
//
