ID Q5BDT7_EMENI Unreviewed; 246 AA.
AC Q5BDT7; C8VS92;
DT 26-APR-2005, integrated into UniProtKB/TrEMBL.
DT 26-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=VPS37 C-terminal domain-containing protein {ECO:0000259|PROSITE:PS51314};
GN ORFNames=ANIA_01293 {ECO:0000313|EMBL:CBF87775.1};
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321 {ECO:0000313|EMBL:CBF87775.1, ECO:0000313|Proteomes:UP000000560};
RN [1] {ECO:0000313|Proteomes:UP000000560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.J., Wortman J.R., Batzoglou S.,
RA Lee S.I., Basturkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M., Hynes M., Paoletti M., Fischer R., Miller B.,
RA Dyer P., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2] {ECO:0000313|Proteomes:UP000000560}
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- SIMILARITY: Belongs to the VPS37 family.
CC {ECO:0000256|ARBA:ARBA00007617}.
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DR EMBL; BN001308; CBF87775.1; -; Genomic_DNA.
DR RefSeq; XP_658897.1; XM_653805.1.
DR AlphaFoldDB; Q5BDT7; -.
DR STRING; 227321.Q5BDT7; -.
DR EnsemblFungi; CBF87775; CBF87775; ANIA_01293.
DR GeneID; 2877072; -.
DR KEGG; ani:AN1293.2; -.
DR VEuPathDB; FungiDB:AN1293; -.
DR eggNOG; ENOG502S268; Eukaryota.
DR HOGENOM; CLU_088665_0_0_1; -.
DR InParanoid; Q5BDT7; -.
DR OMA; SWRKKQT; -.
DR OrthoDB; 2732551at2759; -.
DR Proteomes; UP000000560; Chromosome VIII.
DR GO; GO:0000813; C:ESCRT I complex; IBA:GO_Central.
DR GO; GO:0006612; P:protein targeting to membrane; IBA:GO_Central.
DR GO; GO:0006623; P:protein targeting to vacuole; IBA:GO_Central.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IBA:GO_Central.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR InterPro; IPR037202; ESCRT_assembly_dom.
DR InterPro; IPR009851; Mod_r.
DR PANTHER; PTHR13678; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37; 1.
DR PANTHER; PTHR13678:SF2; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A; 1.
DR Pfam; PF07200; Mod_r; 1.
DR SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR PROSITE; PS51314; VPS37_C; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000000560};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 155..246
FT /note="VPS37 C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51314"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 246 AA; 26985 MW; ED9E35501AEA09E7 CRC64;
MNPNLHADTP PPPPPKPGSH EASRGGTPQV GSPSPTAAQL PQQGQYGLDV TNQYLNPSTV
NPTANGPRPP AIEEGWLPEG IKEKSTIDLQ TILETPSLIS ALSATHPSHH CHQEMLQTLL
KYNQDLANHL LDLQSQLTSL RSSTETLLLQ HQSLEVSWRK KQGEMDSALA PWSPKALYQR
LSAGIAEQEA VCFAVEESFL EGEHHGKASE KEVADWVRRV RAEGAKLAGR REAKARWDEG
RVGGWR
//
