ID Q5BJ18_DANRE Unreviewed; 77 AA.
AC Q5BJ18; A0A8M1NTD2;
DT 12-APR-2005, integrated into UniProtKB/TrEMBL.
DT 12-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 123.
DE SubName: Full=Heat shock factor binding protein 1-like {ECO:0000313|RefSeq:NP_001166105.1};
DE SubName: Full=Heat shock factor-binding protein 1a {ECO:0000313|Ensembl:ENSDARP00000091818};
DE SubName: Full=Zgc:113055 {ECO:0000313|EMBL:AAH91658.1};
GN Name=hsbp1a {ECO:0000313|Ensembl:ENSDARP00000091818,
GN ECO:0000313|RefSeq:NP_001166105.1,
GN ECO:0000313|ZFIN:ZDB-GENE-050320-136};
GN Synonyms=zgc:113055 {ECO:0000313|EMBL:AAH91658.1,
GN ECO:0000313|RefSeq:NP_001166105.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH91658.1};
RN [1] {ECO:0000313|EMBL:AAH91658.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo {ECO:0000313|EMBL:AAH91658.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000091818}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000091818};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSDARP00000091818, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000091818};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [4] {ECO:0000313|RefSeq:NP_001166105.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23593122;
RA Tao T., Shi H., Huang D., Peng J.;
RT "Def functions as a cell autonomous factor in organogenesis of digestive
RT organs in zebrafish.";
RL PLoS ONE 8:E58858-E58858(2013).
RN [5] {ECO:0000313|RefSeq:NP_001166105.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26469318;
RA Elkon R., Milon B., Morrison L., Shah M., Vijayakumar S., Racherla M.,
RA Leitch C.C., Silipino L., Hadi S., Weiss-Gayet M., Barras E., Schmid C.D.,
RA Ait-Lounis A., Barnes A., Song Y., Eisenman D.J., Eliyahu E.,
RA Frolenkov G.I., Strome S.E., Durand B., Zaghloul N.A., Jones S.M.,
RA Reith W., Hertzano R.;
RT "RFX transcription factors are essential for hearing in mice.";
RL Nat. Commun. 6:8549-8549(2015).
RN [6] {ECO:0000313|Ensembl:ENSDARP00000142905}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000142905};
RG Ensembl;
RL Submitted (OCT-2016) to UniProtKB.
RN [7] {ECO:0000313|RefSeq:NP_001166105.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=28252024;
RA Bayes A., Collins M.O., Reig-Viader R., Gou G., Goulding D., Izquierdo A.,
RA Choudhary J.S., Emes R.D., Grant S.G.;
RT "Evolution of complexity in the zebrafish synapse proteome.";
RL Nat. Commun. 8:14613-14613(2017).
RN [8] {ECO:0000313|RefSeq:NP_001166105.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the HSBP1 family.
CC {ECO:0000256|ARBA:ARBA00006349}.
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DR EMBL; CR388045; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC091658; AAH91658.1; -; mRNA.
DR RefSeq; NP_001166105.1; NM_001172634.2.
DR STRING; 7955.ENSDARP00000091818; -.
DR PaxDb; 7955-ENSDARP00000091818; -.
DR Ensembl; ENSDART00000101044.6; ENSDARP00000091818.3; ENSDARG00000069425.6.
DR Ensembl; ENSDART00000173765.2; ENSDARP00000142905.1; ENSDARG00000069425.6.
DR GeneID; 541432; -.
DR KEGG; dre:541432; -.
DR AGR; ZFIN:ZDB-GENE-050320-136; -.
DR CTD; 541432; -.
DR ZFIN; ZDB-GENE-050320-136; hsbp1a.
DR eggNOG; KOG4117; Eukaryota.
DR HOGENOM; CLU_149552_2_0_1; -.
DR OMA; MNSCIGD; -.
DR OrthoDB; 11594at2759; -.
DR TreeFam; TF314005; -.
DR Proteomes; UP000000437; Chromosome 7.
DR Bgee; ENSDARG00000069425; Expressed in brain and 28 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR GO; GO:0070370; P:cellular heat acclimation; IBA:GO_Central.
DR Gene3D; 1.20.5.430; -; 1.
DR InterPro; IPR009643; HS1-bd.
DR PANTHER; PTHR19424; HEAT SHOCK FACTOR BINDING PROTEIN 1; 1.
DR PANTHER; PTHR19424:SF0; HEAT SHOCK FACTOR-BINDING PROTEIN 1-RELATED; 1.
DR Pfam; PF06825; HSBP1; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Stress response {ECO:0000313|RefSeq:NP_001166105.1}.
FT COILED 31..65
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 77 AA; 8680 MW; 766FA98174830AC4 CRC64;
MSEKDPKSSQ DLTVVVQTLL QQMQDKFQTM SDQIIGRIDE MSTRIDDLEK NISDLMTQAG
VEELEEEIKN SETSGTA
//
